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PRODID:-//meduniwien.ac.at//Events//DE
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UID:event-2219-date-3573@meduniwien.ac.at
DTSTAMP:20230906T071211Z
SUMMARY:Ludwig Boltzmann Lecture: Role of Vasa Vasorum in Thoracic Aortic D
 isease: Pathophysiology and Therapeutic Opportunities - Julie A. Phillippi
 \, PhD
DTSTART:20231003T140000
DTEND:20231003T150000
DESCRIPTION:Role of Vasa Vasorum in Thoracic Aortic Disease: Pathophysiolog
 y and Therapeutic Opportunities\n\nJulie A. Phillippi\, PhD\n Associate Pr
 ofessor | UPMC Pellegrini Chair in Cardiothoracic Surgery | Vice Chair for
  Cardiac Research and Director of Postdoctoral Research\, Department of Ca
 rdiothoracic Surgery | Scientific Director- Cardiac Research Laboratory | 
 Program Co-Director\, T32 Cardiothoracic Surgery Research Training Program
  | University of Pittsburgh School of Medicine |\n\nOrganizer:\n Ludwig Bo
 ltzmann Institute for Cardiovascular Research\n\nHost:\n Bruno Podesser\n\
 nAbstract:\n Dr. Phillippi leads an interdisciplinary research team of mic
 rovascular enthusiasts who study the vasa vasorum\, a network of microvess
 els that nourish larger arteries and veins. The team’s main goal is to l
 everage new knowledge of the underlying matrix-mediated mechanisms governi
 ng vasa vasorum (dys)function to develop preventative and less invasive su
 rgical treatments for patients affected by cardiovascular diseases. The Ph
 illippi Cardiac Research Laboratory utilizes surgically obtained human tis
 sue and blood to develop in vitro human disease models at the cell\, tissu
 e\, and whole vessel levels. There is focused attention on the perivascula
 r microenvironment of the adventitia\, vasa vasorum-associated cells\, and
  extracellular matrix (ECM) signaling. In this presentation for the Medica
 l University of Vienna Center for Biomedical Research and Translational Su
 rgery\, Dr. Phillippi will discuss the involvement of vasa vasorum in card
 iovascular disease and share her team’s progress in understanding microv
 ascular remodeling and the influence of biochemical and biophysical ECM cu
 es on vasa vasorum-associated cells. There will be a focus on observations
  from human aneurysmal specimens and the team’s approach to develop vasc
 ular ECM hydrogel biomaterials as in vitro disease models and therapeutics
  to gain a new understanding of human aortic disease from theperspective o
 f the vasa vasorum.
LOCATION:Center for Biomedical Research and Translational Surgery
CLASS:PUBLIC
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