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 Division of Immunopathology
Department of Pathophysiology and Allergy Research
Center of Pathophysiology, Infectiology & Immunology

Medical University of Vienna

Vienna General Hospital, AKH, 3Q
Waehringer Guertel 18-20
A-1090 Vienna, Austria
 

Molecular, immunological and structural characterization of mite allergens for diagnosis, pre-vention and specific immunotherapy.

Publications

  1. Weghofer M, Thomas WR, Pittner G, Horak F, Valenta R, Vrtala S. Comparison of purified Dermatophagoides pteronyssinus allergens and extract by two-dimensional immunoblotting and quantitative immunoglobulin E inhibitions. Clin Exp Allergy. 2005 Oct;35(10):1384-91.
  2. Vrtala S, Focke M, Kopec J, Verdino P, Hartl A, Sperr WR, Fedorov AA, Ball T, Almo S, Valent P, Thalhamer J, Keller W, Valenta R. Genetic engineering of the major timothy grass pollen allergen, Phl p 6, to reduce allergenic activity and preserve immunogenicity. J Immunol. 2007 Aug 1;179(3):1730-9.
  3. Chen KW, Fuchs G, Sonneck K, Gieras A, Swoboda I, Douladiris N, Linhart B, Jankovic M, Pavkov T, Keller W, Papadopoulos NG, Valent P, Valenta R, Vrtala S. Reduction of the in vivo allergenicity of Der p 2, the major house-dust mite allergen, by genetic engineering. Mol Immunol. 2008 May;45(9):2486-98. Epub 2008 Mar 4.
  4. Related Articles , Links Weghofer M, Grote M, Dall'antonia Y, Fernández-Caldas E, Krauth MT, van Hage M, Horak F, Thomas WR, Valent P, Keller W, Valenta R, Vrtala S. Characterization of Folded Recombinant Der p 5, a Potential Diagnostic Marker Allergen for House Dust Mite Allergy. Int Arch Allergy Immunol. 2008 Jun 3;147(2):101-109.
  5. Weghofer M, Thomas WR, Kronqvist M, Mari A, Purohit A, Pauli G, Horak F, Grönlund H, van Hage M, Valenta R, Vrtala S. Variability of IgE reactivity profiles among European mite allergic patients. Eur J Clin Invest. 2008 Dec;38(12):959-65.