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 Division of Immunopathology
Department of Pathophysiology and Allergy Research
Center of Pathophysiology, Infectiology & Immunology

Medical University of Vienna

Vienna General Hospital, AKH, 3Q
Waehringer Guertel 18-20
A-1090 Vienna, Austria
 

Molecular approaches to dissect pathomechanisms of allergy

Publications 

  1. Gieras A, Focke-Tejkl M, Ball T, Verdino P, Hartl A, Thalhamer J, Valenta R. Molecular determinants of allergen-induced effector cell degranulation. J Allergy Clin Immunol. 2007 Feb;119(2):384-90. Epub 2006 Nov 7.
  2. Linhart B, Bigenzahn S, Hartl A, Lupinek C, Thalhamer J, Valenta R, Wekerle T. Costimulation blockade inhibits allergic sensitization but does not affect established allergy in a murine model of grass pollen allergy. J Immunol. 2007 Mar 15;178(6):3924-31.
  3. Rauter I, Krauth MT, Westritschnig K, Horak F, Flicker S, Gieras A, Repa A, Balic N, Spitzauer S, Huss-Marp J, Brockow K, Darsow U, Behrendt H, Ring J, Kricek F, Valent P, Valenta R. Mast cell-derived proteases control allergic inflammation through cleavage of IgE. J Allergy Clin Immunol. 2008 Jan;121(1):197-202. Epub 2007 Sep 29.
  4. Campana R, Mothes N, Rauter I, Vrtala S, Reininger R, Focke-Tejkl M, Lupinek C, Balic N, Spitzauer S, Valenta R. Non-IgE-mediated chronic allergic skin inflammation revealed with rBet v 1 fragments. J Allergy Clin Immunol. 2008 Feb;121(2):528-530.e1.
  5. Lupinek C, Roux KH, Laffer S, Rauter I, Reginald K, Kneidinger M, Blatt K, Ball T, Pree I, Jahn-Schmid B, Allam JP, Novak N, Drescher A, Kricek F, Valent P, Englund H, Valenta R. Trimolecular complex formation of IgE, Fc(epsilon)RI, and a recombinant nonanaphylactic single-chain antibody fragment with high affinity for IgE. J Immunol. 2009 Apr 15;182(8):4817-29.