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       Publications Allergen-hybrids - next generation vaccines for Fagales pollen immunotherapy. Pichler, U., M. Hauser, H. Hofer, M. Himly, E. Hoflehner, M. Steiner, S. Mutschlechner, K. Hufnagl, C. Ebner, A. Mari , P.Briza, B. Bohle, U. Wiedermann, F. Ferreira, M. Wallner. Clin Exp Allergy. Dec 11. doi: 10.1111/cea.12250, 2013
Kinetics, cross-reactivity and specificity of Bet v 1-specific IgG4 antibodies induced by immunotherapy with birch pollen Subbarayal, B., D. Schiller, C. Möbs , N. W. de Jong, C. Ebner, N. Reider, D. Bartel, J. Lidholm, W. Pfützner, R. Gerth van Wijk, S.Vieths and B. Bohle. Allergy 68(11):1377-86. doi: 10.1111/all.12236, 2013
Recombinant Mal d 1 is a reliable diagnostic tool for birch pollen allergen-associated apple allergy. Kollmann, D., M. Geroldinger-Simic, T. Kinaciyan, H. Huber, C. Ebner, J. Lidholm and B. Bohle. J Allergy Clin Immunol,Doi:10.1016/j.jaci.2013.05.030, 2013
Oral exposure to Mal d 1 affects the immune response in birch pollen-allergic patients. Geroldinger-Simic, M., T. Kinaciyan, B. Nagl, U. Baumgartner-Durchschlag, H. Huber, C. Ebner, J. Lidholm, D. Bartel, S. Vieths, B. Jahn-Schmid and B. Bohle. J Allergy Clin Immunol, 131:94. doi: 10.1016/j.jaci.2012.06.039, 2013
A hypoallergenic variant of the major birch pollen allergen shows distinct characteristics in antigen processing and T cell activation. Kitzmüller, C., M. Wallner, S. Deifl, S. Mutschlechner, C. Walterskirchen, G.J. Zlabinger, F. Ferreira and B. Bohle. Allergy, 67:1375. doi: 10.1111/all.12016, 2012
Association of HLA-DR1 with the allergic response to the major mugwort pollen allergen: molecular background. Knapp, B., G. Fischer, D. Van Hemelen, I. Fae, B. Maillere, C. Ebner, W. Schreiner, B. Bohle and B. Jahn-Schmid. BMC Immunol, 13:43, 2012
Human blood basophils do not act as antigen-presenting cells for the major birch pollen allergen Bet v 1. Kitzmüller, C., B. Nagl, S. Deifl, C. Walterskirchen, B. Jahn-Schmid, G. J. Zlabinger and B. Bohle. Allergy, 67:593-600. doi: 10.1111/j.1398-9995.2011.02764.x, 2012
Nitration of the Pollen Allergen Bet v 1.0101 Enhances the Presentation of Bet v 1-derived Peptides by HLA-DR on Human Dendritic Cells. Karle, A.C, G. J. Oostingh, S. Mutschlechner, F. Ferreira, P. Lackner, B. Bohle, G. F. Fischer, A. B. Vogt and A. Duschl. Plos One, 7:e31483, 2012
Humoral and cellular cross-reactivity between Amb a 1, the major ragweed pollen allergen, and its mugwort homolog Art v 6 Jahn-Schmid, B., M. Hauser, N. Wopfner, P. Briza, U. E. Berger R. Asero, C. Ebner, F. Ferreira, and B. Bohle. J Immunol, 188:1559, 2012
Human TCR Transgenic Bet v 1-Specific Th1 Cells Suppress the Effector Function of Bet v 1-Specific Th2 Cells Neunkirchner, A ., V. M. Leb-Reichl, K. G. Schmetterer , S. Mutschlechner, H. J. Kueng, D. Haiderer, K. Schuch, M. Wallner, B. Jahn-Schmid, B. Bohle and W. F. Pickl. J Immunol, 187:4077,2011
Pru p 3, the non-specific lipid transfer protein from peach, dominates the immune response to its homolog in hazelnut Schulten, V., B. Nagl, E. Scala, M. L. Bernardi, A. Mari, M. A. Ciardiello, I. Lauer, S. Scheurer, P. Briza, A. Jürets, F. Ferreira, B. Jahn-Schmid, G. F. Fischer and B. Bohle. Allergy, DOI 10.1111/j.1398-9995.2011.02567, 2011
Birch pollen-related food allergy: Clinical aspects and the role of allergen-specific IgE and IgG4 antibodies Geroldinger-Simic, M., T. Zelniker, W. Aberer, C. Ebner, C. Egger, A. Greiderer, N. Prem, J. Lidholm, B. K. Ballmer- Weber, S. Vieths and B. Bohle. J Allergy Clin Immunol, DOI 10.1016/j.jaci.2010.10.027, 2011
Interaction of Allergens, Major Histocompatibility Complex Molecules, and T Cell Receptors: A 'Ménage à Trois' That Opens New Avenues for Therapeutic Intervention in Type I Allergy Jahn-Schmid, B., W. F. Pickl and B. Bohle. Int Arch Allergy Immunol, 156(1):27-42, 2011
Reshaping the Bet v 1-fold modulates T-helper polarization Wallner, M., M. Hauser, M. Himly , N. Zaborsky, S. Mutschlechner, A. Harrer, C. Asam, U. Pichler, R. van Ree, P. Briza, J. Thalhamer, B. Bohle, G. Achatz, and F. Ferreira. J Allergy Clin Immunol, Jun;127(6):1571-8.e9, 2011
Protein unfolding strongly modulates the allergenicity and immunogenicity of Pru p 3, the major peach allergen Toda, M., G. Reese, G. Gadermaier , V. Schulten, I. Lauer, M. Egger, P. Briza , S. Randow, S. Wolfheimer, V. Kigongo, M. Del Mar San Miguel Moncin, K. Fötisch, B. Bohle, S. Vieths and S. Scheurer. J Allergy Clin Immunol, May 13. [Epub ahead of print] PMID: 21571358 [PubMed - as supplied by publisher], 2011
Bet v 1-specific TCR/Foxp3 transgenic T-cells suppress Bet v 1-specific T- cell effector function in an activation dependent manner Schmetterer, K., D. Haiderer, V. M. Leb-Reichl, A. Neunkirchner, B. Jahn-Schmid, H.J. Küng, K. Schuch, P. Steinberger, B. Bohle and W. F. Pickl. J Allergy Clin Immunol.127:238, 2011
Assessing Protein Immunogenicity with a Dendritic Cell Line-Derived Endolysosomal Degradome Egger, M., A. Jürets, M. Wallner, P. Briza, S. Ruzek, S. Hainzl, U. Pichler, C. Kitzmüller, B. Bohle, C. G. Huber and F. Ferreira. PLoS One, Feb 16;6(2):e17278, 2011
Sclerostin serum levels correlate positively with bone mineral density and microarchitecture in haemodialysis patients Cejka, D., A. Ja¨ger-Lansky, H. Kieweg, M. Weber, C. Bieglmayer, D. G. Haider, D. Diarra, J. Patsch, F. Kainberger, B. Bohle and M. Haas. Nephrol Dial Transplant, May 25. [Epub ahead of print] PMID: 21613383, 2011
Expression of a Major Plant Allergen as Membrane-Anchored and Secreted Protein in Human Cells with Preserved T Cell and B Cell Epitopes Baranyi, U., M. Gattringer, A. Boehm, K. Marth, M. Focke-Tejkl, B. Bohle, K. Blatt, P. Valent, R. Valenta, and T. Wekerle. Int Arch Allergy Immunol, 156:259-266 (DOI: 10.1159/000323733), 2011
Naturally processed T cell-activating peptides of the major birch pollen allergen Mutschlechner, S., M. Egger, P. Briza, M. Wallner, P. Lackner, A. Karle, AB. Vogt, GF. Fischer, B. Bohle and F. Ferreira. J Allergy Clin Immunol., 125(3):711-8, 718.e1-718.e2, 2010
Schmetterer, KG., MG. Seidl, U. Körmöczi, A. Rottal, K. Schwarz, S. Matthes-Martin, P. Steinberger and WF. Pickl Two newly diagnosed HLA class II deficient patients identified by rapid vector-based complementation reveal dicoordinate invariant chain expression levels Int Arch Allergy Immunol.,152(4):390-400, 2010
Genetic allergen modification in the development of novel approaches to specific immunotherapy. Clinical and Experimental Allergy Mutschlechner, S., S. Deifl and B. Bohle Clin Exp Allergy, 39:1635, 2009
Modulation of allergen-specific T-lymphocyte function by virus-like particles decorated with HLA class II molecules. Leb, VM., B. Jahn-Schmid, HJ. Kueng, KG. Schmetterer, D. Haiderer, A. Neunkirchner, GF. Fischer, A. Hartl, J. Thalhamer, P. Steinberger, B. Bohle, B. Seed and WF.Pickl J Allergy Clin Immunol.,124:121, 2009
Characterization of the allergic T-cell response to Pru p 3, the nonspecific lipid transfer protein in peach Schulten, V., A. Radakovics, C. Hartz, A. Mari, S. Vazquez-Cortes, M. Fernandez-Rivas, I. Lauer, B. Jahn-Schmid, T. Eiwegger, S. Scheurer and B. Bohle J Allergy Clin Immunol., 124:100, 2009
Natural self-assembly of allergen-S-layer fusion proteins is no prerequisite for reduced allergenicity and T cell stimulatory capacity
Knapp, B., U. Omasits, B. Bohle, B. Maillere, C. Ebner, W. Schreiner and B. Jahn-Schmid Mol Immunol., 46:1839, 2009
Immunologic characterization of isoforms of Car b 1 and Que a 1, the major hornbeam and oak pollen allergens Wallner, M., A. Erler, M. Hauser, E. Klinglmayr, G. Gadermaier, L. Vogel, A. Mari,B. Bohle, P. Briza and F. Ferreira Allergy, 64:452, 2009
Characterization of HLA-class II / peptide-TCR interactions of the immunodominant T cell Epitope in Art v 1, the major mugwort pollen allergen
Molecular and functional analysis of the antigen receptor of Art v 1-specific helper T lymphocytes
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