The short-chain dehydrogenase/reductase family (SDR) is a very large family of enzymes, most of which are known to be NAD or NADP-dependent oxidoreductases .
The fungal allergens Alt a 8 from Alternaria alternata and Cla h 8 from Cladosporium herbarum are mannitol dehydrogenases .
Family-defining Pfam domains (at least one of these domains is present in each family member):
|Pfam domain||Pfam clan|
|PF00106||short chain dehydrogenase||CL0063||FAD/NAD(P)-binding Rossmann fold Superfamily|
|PF13561||Enoyl-(Acyl carrier protein) reductase||CL0063||FAD/NAD(P)-binding Rossmann fold Superfamily|
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