Enolases (2-phospho-D-glycerate hydrolases) are essential glycolytic enzymes that catalyze the interconversion of 2-phosphoglycerate and phosphoenolpyruvate .
Allergens from this family
Enolases are important allergens from various molds and some plants. They were shown to exhibit cross-reactivity to other fungal and plant enolases [2, 3, 4].
Mechanism of enolase: the crystal structure of asymmetric dimer enolase-2-phospho-D-glycerate/enolase-phosphoenolpyruvate at 2.0 A resolution.
Biochemistry 1997, 36, 12526-34. [PubMed] [Full Text]
IgE-binding epitopes of enolases, a class of highly conserved fungal allergens.
J Allergy Clin Immunol 2000, 106, 887-95. [PubMed] [Full Text]
cDNA cloning and immunological characterization of a newly identified enolase allergen from Penicillium citrinum and Aspergillus fumigatus.
Int Arch Allergy Immunol 2002, 127, 181-90. [PubMed] [Full Text]
Hev b 9, an enolase and a new cross-reactive allergen from hevea latex and molds. Purification, characterization, cloning and expression.
Eur J Biochem 2000, 267, 7006-14. [PubMed]
Links to Pfam
Family-defining Pfam domains (at least one of these domains is present in each family member):
Enolase, C-terminal TIM barrel domain
Enolase like TIM barrel
Enolase, N-terminal domain
Enolase N-terminal domain-like superfamily
Links to Wikipedia
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