Collagens are extracellular structural proteins involved in formation of connective tissue structure. The sequence consists predominantly or repeats of G-X-Y and the polypeptide chains form a triple helix. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure.
Bovine gelatin present in vaccines was shown to cause allergic reactions .
Family-defining Pfam domains (at least one of these domains is present in each family member):
|Pfam domain||Pfam clan|
|PF01391||Collagen triple helix repeat (20 copies)||-|
|PF01410||Fibrillar collagen C-terminal domain||CL0422||Fibrinogen C-terminal domain-like|
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