This family consists of various glycoproteins from plants. Patatin accounts for up to 40% of total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids [1]. Members of this family have also been found in vertebrates.
Patatin is a major potato allergen. Its homology and cross-reactivity to the major Hevea brasiliensis latex allergen Hev b 7 explains the observation of potatoes being one of the plant foods involved in the latex-fruit syndrome [2].
Family-defining Pfam domains (at least one of these domains is present in each family member):
| Pfam domain | Pfam clan | ||
| PF01734 | Patatin-like phospholipase | CL0323 | Patatin/FabD/lysophospholipase-like superfamily |
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