This family contains alpha-helical proteins of unknown function found exclusively in mites .
Two groups of mite allergens belong to this family. Group 5 allergens are major allergens, especially important in the tropical species Blomia tropicalis (Blo t 5). Cross-reactivity between group 5 allergens from different mite species appears to be low . Group 21 allergens are major allergens that showed low to moderate cross-reactivity to group 5 allergens .
Family-defining Pfam domains (at least one of these domains is present in each family member):
|Pfam domain||Pfam clan|
|PF11642||Mite allergen Blo t 5||-|
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