2023
Colucci E, Anshari ZR, Patiño-Ruiz MF, Nemchinova M, Whittaker J, Slotboom DJ, Guskov A.
Mutation in glutamate transporter homologue GltTk provides insights into pathologic mechanism of episodic ataxia 6.
Nat Commun. 2023 Mar 31;14(1):1799. doi: 10.1038/s41467-023-37503-y. PMID: 37002226; PMCID: PMC10066184.
Bazzone A, Zerlotti R, Barthmes M, Fertig N.
Functional characterization of SGLT1 using SSM-based electrophysiology: Kinetics of sugar binding and translocation.
Front Physiol. 2023 Feb 7;14:1058583. doi: 10.3389/fphys.2023.1058583. PMID: 36824475; PMCID: PMC9941201.
Romanazzi T, Zanella D, Bhatt M, Di Iacovo A, Galli A, Bossi E.
Bile acid interactions with neurotransmitter transporters.
Front Cell Neurosci. 2023 Apr 26;17:1161930. doi: 10.3389/fncel.2023.1161930. PMID: 37180953; PMCID: PMC10169653.
Bhatt M, Gauthier-Manuel L, Lazzarin E, Zerlotti R, Ziegler C, Bazzone A, Stockner T, Bossi E.
A comparative review on the well-studied GAT1 and the understudied BGT-1 in the brain.
Front Physiol. 2023 Apr 13;14:1145973. doi: 10.3389/fphys.2023.1145973. PMID: 37123280; PMCID: PMC10137170.
Bhatt M, Di Iacovo A, Romanazzi T, Roseti C, Bossi E.
Betaine - The dark knight of the brain.
Basic Clin Pharmacol Toxicol. 2023 Feb 3. doi: 10.1111/bcpt.13839. Epub ahead of print. PMID: 36735640.
2022
Luethi D, Maier J, Rudin D, Szöllősi D, Angenoorth TJF, Stankovic S, Schittmayer M, Burger I, Yang JW, Jaentsch K, Holy M, Das AK, Brameshuber M, Camacho-Hernandez GA, Casiraghi A, Newman AH, Kudlacek O, Birner-Gruenberger R, Stockner T, Schütz GJ, Sitte HH.
Phosphatidylinositol 4,5-bisphosphate (PIP2) facilitates norepinephrine transporter dimerization and modulates substrate efflux.
Commun Biol. 2022 Nov 17;5(1):1259. doi: 10.1038/s42003-022-04210-1. PMID: 36396757; PMCID: PMC9672106.
Khanppnavar B, Maier J, Herborg F, Gradisch R, Lazzarin E, Luethi D, Yang JW, Qi C, Holy M, Jäntsch K, Kudlacek O, Schicker K, Werge T, Gether U, Stockner T, Korkhov VM, Sitte HH.
Structural basis of organic cation transporter-3 inhibition.
Nat Commun. 2022 Nov 7;13(1):6714. doi: 10.1038/s41467-022-34284-8. PMID: 36344565; PMCID: PMC9640557.
Bhatt M, Di Iacovo A, Romanazzi T, Roseti C, Cinquetti R, Bossi E.
The "www" of Xenopus laevis Oocytes: The Why, When, What of Xenopus laevis Oocytes in Membrane Transporters Research.
Membranes (Basel). 2022 Sep 25;12(10):927. doi: 10.3390/membranes12100927. PMID: 36295686; PMCID: PMC9610376.
Gradisch R, Szöllősi D, Niello M, Lazzarin E, Sitte HH, Stockner T.
Occlusion of the human serotonin transporter is mediated by serotonin-induced conformational changes in the bundle domain.
J Biol Chem. 2022 Mar;298(3):101613. doi: 10.1016/j.jbc.2022.101613. Epub 2022 Jan 21. PMID: 35065961; PMCID: PMC8867121.
Maity S, Trinco G, Buzón P, Anshari ZR, Kodera N, Ngo KX, Ando T, Slotboom DJ, Roos WH.
High-speed atomic force microscopy reveals a three-state elevator mechanism in the citrate transporter CitS.
Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2113927119. doi: 10.1073/pnas.2113927119. PMID: 35101979; PMCID: PMC8833178.
2021
Plenge P, Yang D, Salomon K, Laursen L, Kalenderoglou IE, Newman AH, Gouaux E, Coleman JA, Loland CJ.
The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter.
Nat Commun. 2021 Aug 20;12(1):5063. doi: 10.1038/s41467-021-25363-3. PMID: 34417466; PMCID: PMC8379219.
Nadal-Gratacós N, Alberto-Silva AS, Rodríguez-Soler M, Urquizu E, Espinosa-Velasco M, Jäntsch K, Holy M, Batllori X, Berzosa X, Pubill D, Camarasa J, Sitte HH, Escubedo E, López-Arnau R.
Structure-Activity Relationship of Novel Second-Generation Synthetic Cathinones: Mechanism of Action, Locomotion, Reward, and Immediate-Early Genes.
Front Pharmacol. 2021 Oct 26;12:749429. doi: 10.3389/fphar.2021.749429. PMID: 34764870; PMCID: PMC8576102.
Ozvoldik K, Stockner T, Rammner B, Krieger E.
Assembly of Biomolecular Gigastructures and Visualization with the Vulkan Graphics API.
J Chem Inf Model. 2021 Oct 25;61(10):5293-5303. doi: 10.1021/acs.jcim.1c00743. Epub 2021 Sep 16. PMID: 34528431; PMCID: PMC8549067.
Lerner E, Barth A, Hendrix J, Ambrose B, Birkedal V, Blanchard SC, Börner R, Sung Chung H, Cordes T, Craggs TD, Deniz AA, Diao J, Fei J, Gonzalez RL, Gopich IV, Ha T, Hanke CA, Haran G, Hatzakis NS, Hohng S, Hong SC, Hugel T, Ingargiola A, Joo C, Kapanidis AN, Kim HD, Laurence T, Lee NK, Lee TH, Lemke EA, Margeat E, Michaelis J, Michalet X, Myong S, Nettels D, Peulen TO, Ploetz E, Razvag Y, Robb NC, Schuler B, Soleimaninejad H, Tang C, Vafabakhsh R, Lamb DC, Seidel CA, Weiss S.
FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices.
Elife. 2021 Mar 29;10:e60416. doi: 10.7554/eLife.60416. PMID: 33779550; PMCID: PMC8007216.
NeuroTrans has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Actions grant agreement no. 860954.