NeuroTrans - Past Meetings

Alberto e Silva Ana Sofia
Characterization of the molecular mode of action of new psychoactive substances (NPS)

Alves da Silva Leticia
Microsecond-long molecular dynamic simulation from human dopamine transporter in outward-open state

Anshari Zaid R.
Biochemical and biophysical characterization of proton/glutamate-aspartate symporter

Bhatt Manan
Betaine: The Dark Knight of CNS!?!

Brugnoli Francesca R.
Development of a cell perfusion station for controller compound delivery

Campana Anna
Functional characterization of novel disease-associated mutations in the dopamine transporter

Daminato Alberto
Use of Saturation Transference Difference NMR to investigate ligand binding to LeuT

Estengre Pérez Judith
First steps towards visualising a neurotransmitter transporter in action

Gauthier-Manuel Laure
GABA transporters, Back to the future with the GAT1.

Kalenderoglou Iris E.
Allosteric inhibition of the serotonin transporter: the case of the antidepressant vilazodone

Kapiki Despoina
Protein fluorophore labeling for probing conformational dynamics

Lazzarin Erika
Towards a comprehensive model of GABA transporter function

Tsalagradas Petros
Overexpression, isolation, purification, and spin-labeling of three novel LeuT cysteine mutants for downstream EPR analysis

Turaev Anton
Novel methods to measure parameters of LeuT-ligand interactions

Zerlotti Rocco
Solid supported membrane (SSM) electrophysiology for hGAT1 characterization

Alberto e Silva Ana Sofia
Analysis of the Dopamine and Serotonin Transporter Substrate Selectivity

Alves da Silva Leticia
The atomic features that underlie the occlusion mechanism of the human dopamine transporter

Anshari Zaid R.
Functional analysis of the glutamate/aspartate-proton symporter GltP

Bhatt Manan
Another substrate of GABA Transporter 1 (GAT1), the novel therapeutic Betaine!

Brugnoli Francesca R.
Microfluidic platform for screening of compounds on monoamine transporters

Campana Anna
Systematic characterization of human dopamine transporter missense mutations from a Danish cohort of psychiatric patients

Daminato Alberto
NMR investigation of Neurotransmitter-Sodium Symporters: a case study of Leucine Transporter

Estengre Pérez Judith
Towards Directly Visualising Conformational Changes in the Sodium Symporter Family

Kalenderoglou Iris E.
Visualizing the binding mode of the antidepressant vilazodone on the serotonin transporter

Lazzarin Erika
Characterizing sodium binding to the human GABA transporter hGAT1

Tsalagradas Petros
Insights on the conformational dynamics of three LeuT cysteine mutants using pulsed EPR spectroscopy

Turaev Anton
Spectral shift technology to measure transporter-ligand interaction.

Zerlotti Rocco
Individual charge translocations upon GABA, Na+ and Cl- binding to human GAT-1 indicate conformational flexibility

Alberto e Silva Ana Sofia
MDMA: insights on the methylenedioxyphenyl group bioisosteric replacement

Alves da Silva Leticia
Kinetic model and free energy landscape of 5-HT-induced hSERT occlusion

Anshari Zaid R.
Determination of Proton Coupling Stoichiometry of The Glutamate/Aspartate Proton Symporter GltP

Bhatt Manan
The relationship of GAT1 with its substrates GABA and betaine

Brugnoli Francesca R.
Microfluidic platform for screening compounds on monoamine transporters

Campana Anna
Characterizing human dopamine transporter missense mutants from psychiatric patients: insights into DAT-mediated dopamine efflux.

Daminato Alberto
NMR investigation of Neurotransmitter-Sodium Symporters: a case study of Leucine Transporter

Gauthier-Manuel Laure
Interaction of GABA and betaine in GABA transporter 1 wild type and mutants

Estengre Pérez Judith
Behind the scenes: preparing time-resolved structural studies

Kalenderoglou Iris E.
Visualizing the binding mode of the antidepressant vilazodone on the serotonin transporter.

Kapiki Despoina
Single-molecule studies of secondary-active transporters and their environmental dependence

Lazzarin Erika
Characterizing sodium binding to the human GABA transporter hGAT1

Tsalagradas Petros
Insights on the conformational dynamics of the LeuT amino-acid transporter using advanced EPR spectroscopy

Turaev Anton
Novel isothermal fluorescent spectral shift method to measure transporter-ligand interaction

Zerlotti Rocco
Functional characterization of human GAT-1 through solid-supported membrane electrophysiology

Alberto e Silva Ana Sofia
Monoamine transporters: analysis of substrate selectivity and new psychoactive substances

Alves da Silva Leticia
Free energy profile of the substrate-induced occlusion of the human serotonin transporter

Anshari Zaid R.
The glutamate/aspartate-proton symporter GltP or generation of proton motive force in synthetic vesicles

Bhatt Manan
Betaine is a secondary substrate of GAT1 that can regulate extracellular GABA.

Brugnoli Francesca R.
Development of microfluidic systems for biological applications

Campana Anna
Shaping molecular phenotypes of dopamine - transporter missense mutants from psychiatric patients

Daminato Alberto
NMR investigation of Leucine Transporter

Estengre Pérez Judith
What an electric field can do for structural biology?

Gauthier-Manuel Laure
Update on GAT1 structure and function

Kalenderoglou Iris E.
Structural Basis of Serotonin Reuptake Inhibition by a Dual-Mode Orthosteric/Allosteric Antidepresssant

Kapiki Despoina
Single-molecule FRET as a tool for investigating the structural bases and inhibition of PsaA metal transport

Lazzarin Erika
An antenna for sodium sensing and transport regulation in GABA transporter GAT1

Tsalagradas Petros
Study of LeuT using EPR spectroscopy

Turaev Anton
Fluorescence spectral shift-based method to study transporter proteins

Zerlotti Rocco
Identifying transport currents in SSME

Alberto e Silva Ana Sofia
Molecular mode of action of new ecstasy analogues: methylenedioxyphenyl group bioisosteric replacement

Alves da Silva Leticia
Unravelling the free energy landscape and key residues involved in SERT occlusion: insights from molecular dynamics simulations

Anshari Zaid R.
Functional analysis of the glutamate/aspartate-proton symporter GltP

Bhatt Manan
Impact of betaine on GABA transport via GABA transporter 1 (GAT1)

Campana Anna
Modulation of dopamine transporter function by zinc in functionally impaired neuropsychiatric disease mutants

Daminato Alberto
Uncovering a new substrate binding site in the neurotransmitter/sodium symporter homologue LeuT

Kalenderoglou Iris E.
Structural Basis of Serotonin Reuptake Inhibition by a Dual-Mode Orthosteric/Allosteric Antidepressant

Lazzarin Erika
Refining the interaction of GAT1 with sodium ions: from efficient recruitment to stabilisation of substrate and conformation.

Turaev Anton
Novel isothermal fluorescent spectral shift-based method to study membrane transporters.

Zerlotti Rocco
Functional characterization of human GAT-1 through solid supported membrane electrophysiology

All NeuroTrans ESRs presented their work in a scientific poster in addition to their talks.

Alberto e Silva Ana Sofia
Molecular mode of action of new ecstasy analogues: methylenedioxyphenyl group bioisosteric replacement

Alves da Silva Leticia
Unravelling the free energy landscape and key residues involved in SERT occlusion: insights from molecular dynamics simulations

Anshari Zaid R.
Functional analysis of the glutamate/aspartate-proton symporter GltP

Bhatt Manan
Impact of betaine on GABA transport via GABA transporter 1 (GAT1)

Brugnoli Francesca R.
Microfluidic system for automated cellular perfusion: screening compounds on monoamine transporters

Campana Anna
Modulation of dopamine transporter function by zinc in functionally impaired neuropsychiatric disease mutants

Daminato Alberto
Uncovering a new substrate binding site in the neurotransmitter/sodium symporter homologue LeuT

Gauthier-Manuel Laure
GABA Transporter 1 WT and mutants jumping from electrophysiology to structural biology.

Kalenderoglou Iris E.
Structural Basis of Serotonin Reuptake Inhibition by a Dual-Mode Orthosteric/Allosteric Antidepressant

Kapiki Despoina
Probing structural dynamics of BetP osmosensory mechanism with Single molecule FRET.

Lazzarin Erika
Refining the interaction of GAT1 with sodium ions: from efficient recruitment to stabilisation of substrate and conformation.

Turaev Anton
Novel isothermal fluorescent spectral shift-based method to study membrane transporters.

Zerlotti Rocco
Functional characterization of human GAT-1 through solid supported membrane electrophysiology