AF009: Globin

List allergens from this family:

Routes of exposure:
Include only IUIS approved allergens.

Biochemical properties

Globins are heme-containing proteins involved in binding and/or transport of oxygen. The major groups of globins are hemoglobins and myoglobins from vertebrates, invertebrate globins, leghemoglobins from plants, and flavohemoproteins from bacteria [1].

Allergens from this family

Allergenic members of the globin family include bovine myoglobin, a minor beef allergen [2] and hemoglobins from several midge species [3].



  1. Lecomte JT, Vuletich DA, Lesk AM:
    Structural divergence and distant relationships in proteins: evolution of the globins.
    Curr Opin Struct Biol 2005, 15, 290-301. [PubMed] [Full Text]
  2. Fuentes MM, Palacios R, Garces M, Caballero ML, Moneo I:
    Isolation and characterization of a heat-resistant beef allergen: myoglobin.
    Allergy 2004, 59, 327-31. [PubMed] [Full Text]
  3. van Kampen V, Liebers V, Czuppon A, Baur X:
    Chironomidae hemoglobin allergy in Japanese, Swedish, and German populations.
    Allergy 1994, 49, 9-12. [PubMed]


Links to Pfam

Family-defining Pfam domains (at least one of these domains is present in each family member):

Pfam domain Pfam clan
PF00042 Globin CL0090 Globin-like

Links to Wikipedia


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