AF047: Catalase

List allergens from this family:

Routes of exposure:
Include only IUIS approved allergens.

Biochemical properties

Catalases are antioxidant enzymes that catalyse the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects. Most catalases are monofunctional, haem-containing enzymes, although there are also bifunctional haem-containing peroxidase/catalases that are closely related to plant peroxidases, and non-haem, manganese-containing catalases that are found in bacteria [1].

Allergens from this family

Allergenic catalases were described in several fungal species [2, 3].



  1. Chelikani P, Fita I, Loewen PC:
    Diversity of structures and properties among catalases.
    Cell Mol Life Sci 2004, 61, 192-208. [PubMed] [Full Text]
  2. Chiu LL, Lee KL, Lin YF, Chu CY, Su SN, Chow LP:
    Secretome analysis of novel IgE-binding proteins from Penicillium citrinum.
    Proteomics Clin Appl 2008, 2, 33-45. [PubMed] [Full Text]
  3. Ward MD, Donohue MJ, Chung YJ, Copeland LB, Shoemaker JA, Vesper SJ, Selgrade MK:
    Human serum IgE reacts with a Metarhizium anisopliae fungal catalase.
    Int Arch Allergy Immunol 2009, 150, 343-51. [PubMed] [Full Text]


Links to Pfam

Family-defining Pfam domains (at least one of these domains is present in each family member):

Pfam domain Pfam clan
PF00199 Catalase -
PF06628 Catalase-related immune-responsive -

Links to Wikipedia


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