AF058: Ribosomal protein L3

List allergens from this family:

Routes of exposure:
Include only IUIS approved allergens.

Biochemical properties

Ribosomal protein L3 is one of the constituents of the large ribosomal subunit. In Escherichia coli, L3 is known to bind to the 23S rRNA and may participate in the formation of the peptidyltransferase center of the ribosome [1].

Allergens from this family

Asp f 23, an IgE binding L3 protein from Aspergillus fumigatus was isolated from a cDNA library using a pool of sera from patients with allergic bronchopulmonary aspergillosis [2].



  1. Petrov A, Meskauskas A, Dinman JD:
    Ribosomal protein L3: influence on ribosome structure and function.
    RNA Biol 2004, 1, 59-65. [PubMed]
  2. Saxena S, Madan T, Muralidhar K, Sarma PU:
    cDNA cloning, expression and characterization of an allergenic L3 ribosomal protein of Aspergillus fumigatus.
    Clin Exp Immunol 2003, 134, 86-91. [PubMed]


Links to Pfam

Family-defining Pfam domains (at least one of these domains is present in each family member):

Pfam domain Pfam clan
PF00297 Ribosomal protein L3 CL0575 Translation proteins of Elongation Factors superfamily

Links to Wikipedia


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