AF066: Haemocyanin

List allergens from this family:

Routes of exposure:
Include only IUIS approved allergens.

Biochemical properties

Haemocyanins are copper-containing oxygen transport proteins found in the haemolymph of many invertebrates [1].

Allergens from this family

Per a 3 and Bla g 3 American and German cockroach belong to this family [2].



  1. Dolashka-Angelova P, Stevanovic S, Dolashki A, Devreese B, Tzvetkova B, Voelter W, Van Beeumen J, Salvato B:
    A challenging insight on the structural unit 1 of molluscan Rapana venosa hemocyanin.
    Arch Biochem Biophys 2007, 459, 50-8. [PubMed] [Full Text]
  2. Wu CH, Lee MF, Tseng CY:
    IgE-binding epitopes of the American cockroach Per a 3 allergen.
    Allergy 2003, 58, 986-92. [PubMed]


Links to Pfam

Family-defining Pfam domains (at least one of these domains is present in each family member):

Pfam domain Pfam clan
PF00372 Hemocyanin, copper containing domain CL0205 Di-copper centre-containing domain
PF03722 Hemocyanin, all-alpha domain -
PF03723 Hemocyanin, ig-like domain -

Links to Wikipedia


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