This family contains extracellular plant pollen glycoproteins of about 145 residues in length that contain six conserved cysteine residues. Their biological function is unknown.
The prototypic member of this family is the major olive pollen allergen, Ole e 1. This allergen binds IgE from 90% of olive pollen allergic patients' sera . Homologous allergens were identified in other trees from the family Oleaceae (ash, lilac, privet), from grass pollen (group 11 grass pollen allergens), and from weed pollen (plantain, lamb's quarters). These allergens are glycosylated, and the glycan moieties take part in IgE binding . It was shown that IgE cross-reactivity among Ole e 1-related allergens does not extend beyond plant family borders .
Family-defining Pfam domains (at least one of these domains is present in each family member):
|Pfam domain||Pfam clan|
|PF01190||Pollen proteins Ole e I like||-|
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