A number of mammalian lipid-binding serum glycoproteins belong to this family. They include the lipopolysaccharide-binding protein (LBP), the bactericidal permeability-increasing protein (BPI), the cholesteryl ester transfer protein (CETP) the phospholipid transfer protein (PLTP), and the palate, lung and nasal epithelium carcinoma-associated protein (PLUNC). These proteins consist of N- and C-terminal domains, which share a similar two-layer α/β structure, but show little sequence identity to each other .
The horse dander allergen Equ c 4 (a fragment of which was previously named Equ c 5) is a latherin, a surfactant protein in sweat .
Family-defining Pfam domains (at least one of these domains is present in each family member):
|Pfam domain||Pfam clan|
|PF01273||LBP / BPI / CETP family, N-terminal domain||-|
If you have updates or corrections for this entry, please contact the site administrator: email@example.com .