AF090: Oleosin

List allergens from this family:

Routes of exposure:
Include only IUIS approved allergens.

Biochemical properties

Oleosins are the proteinaceous components of plants' lipid storage bodies called oil bodies [1]. Oil bodies are small droplets (0.2 to 1.5 µm in diameter) containing mostly triacylglycerol that are surrounded by a phospholipid/oleosin annulus. Oleosins may have a structural role in stabilizing the lipid body during desiccation of the seed. They may also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth.

Allergens from this family

Allergenic oleosins were identified in legumes, nuts, and seeds [2, 3, 4].



  1. Capuano F, Beaudoin F, Napier JA, Shewry PR:
    Properties and exploitation of oleosins.
    Biotechnol Adv 2007, 25, 203-6. [PubMed] [Full Text]
  2. Schwager C, Kull S, Krause S, Schocker F, Petersen A, Becker WM, Jappe U:
    Development of a novel strategy to isolate lipophilic allergens (oleosins) from peanuts.
    PLoS One 2015, 10, e0123419. [PubMed] [Full Text]
  3. Leduc V, Moneret-Vautrin DA, Tzen JT, Morisset M, Guerin L, Kanny G:
    Identification of oleosins as major allergens in sesame seed allergic patients.
    Allergy 2006, 61, 349-56. [PubMed] [Full Text]
  4. Akkerdaas JH, Schocker F, Vieths S, Versteeg S, Zuidmeer L, Hefle SL, Aalberse RC, Richter K, Ferreira F, van Ree R:
    Cloning of oleosin, a putative new hazelnut allergen, using a hazelnut cDNA library.
    Mol Nutr Food Res 2006, 50, 18-23. [PubMed] [Full Text]


Links to Pfam

Family-defining Pfam domains (at least one of these domains is present in each family member):

Pfam domain Pfam clan
PF01277 Oleosin -

Links to Wikipedia


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