AF112: Plastocyanin

List allergens from this family:

Routes of exposure:
Include only IUIS approved allergens.

Biochemical properties

Blue (type-1) copper proteins are small proteins which bind a single copper atom and which are characterized by an intense electronic absorption band near 600 nm. The best known members of this family are the plant chloroplastic plastocyanins, which exchange electrons with cytochrome c6, and the distantly related bacterial azurins, which exchange electrons with cytochrome c551 [1].

Allergens from this family

The only allergenic member of this family is Amb a 3 from ragweed pollen [2].



  1. Ryden LG, Hunt LT:
    Evolution of protein complexity: the blue copper-containing oxidases and related proteins.
    J Mol Evol 1993, 36, 41-66. [PubMed]
  2. Atassi H, Atassi MZ:
    Antibody recognition of ragweed allergen Ra3: localization of the full profile of the continuous antigenic sites by synthetic overlapping peptides representing the entire protein chain.
    Eur J Immunol 1986, 16, 229-35. [PubMed] [Full Text]


Links to Pfam

Family-defining Pfam domains (at least one of these domains is present in each family member):

Pfam domain Pfam clan
PF00127 Copper binding proteins, plastocyanin/azurin family CL0026 Multicopper oxidase-like domain
PF02298 Plastocyanin-like domain CL0026 Multicopper oxidase-like domain

Links to Wikipedia


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