AF121: BCL7 family

List allergens from this family:

Routes of exposure:
Include only IUIS approved allergens.

Biochemical properties

The members of this family contain a conserved N-terminal domain. The functions of BCL7 proteins are unknown, though they may be involved in early development [1].

Allergens from this family

Human BCL7B was identified as an autoallergen for atopic dermatitis patients [2].



  1. Jadayel DM, Osborne LR, Coignet LJ, Zani VJ, Tsui LC, Scherer SW, Dyer MJ:
    The BCL7 gene family: deletion of BCL7B in Williams syndrome.
    Gene 1998, 224, 35-44. [PubMed]
  2. Natter S, Seiberler S, Hufnagl P, Binder BR, Hirschl AM, Ring J, Abeck D, Schmidt T, Valent P, Valenta R:
    Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients.
    FASEB J 1998, 12, 1559-69. [PubMed]


Links to Pfam

Family-defining Pfam domains (at least one of these domains is present in each family member):

Pfam domain Pfam clan
PF04714 BCL7, N-terminal conserver region -


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