AF126: Insect venom phospholipase A2

List allergens from this family:

Routes of exposure:
Include only IUIS approved allergens.

Biochemical properties

Phospholipase A2 (PLA2) catalyzes the hydrolysis of phopholipids at C2 of the glycerol moiety. This family consists of several phospholipase A2 like proteins mostly from insects.

Allergens from this family

This family contains the group 1 major allergens from bees and bumblebees [1]. They are not related to PLA1 allergens (AllFam:AF037) from vespids.



  1. Hoffman DR:
    Hymenoptera venom allergens.
    Clin Rev Allergy Immunol 2006, 30, 109-28. [PubMed]


Links to Pfam

Family-defining Pfam domains (at least one of these domains is present in each family member):

Pfam domain Pfam clan
PF05826 Phospholipase A2 CL0629 Phospholipase A2 superfamily

Links to Wikipedia


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