AF158: Cellulase family A

List allergens from this family:

Routes of exposure:
Include only IUIS approved allergens.

Biochemical properties

The microbial degradation of cellulose and xylans requires several types of enzymes. Fungi and bacteria produce a spectrum of cellulolytic enzymes (cellulases) and xylanases which, on the basis of sequence similarities, can be classified into several families. One of these is known as the cellulase family A or as the glycosyl hydrolases family 5. This family comprises enzymes with several known activities: endoglucanase, beta-mannanase, exo-1,3-glucanase, endo-1,6-glucanase, xylanase, and endoglycoceramidase.

Allergens from this family

Cha o 3 is a minor allergen from Japanese cedar Chamaecyparis obtusa pollen.


Links to Pfam

Family-defining Pfam domains (at least one of these domains is present in each family member):

Pfam domain Pfam clan
PF00150 Cellulase (glycosyl hydrolase family 5) CL0058 Tim barrel glycosyl hydrolase superfamily

Links to Wikipedia


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