AF166: Serine carboxypeptidase

List allergens from this family:

Routes of exposure:
Include only IUIS approved allergens.

Biochemical properties

All known carboxypeptidases are either metallo carboxypeptidases or serine carboxypeptidases. The serine carboxypeptidases belong to the MEROPS family S10 and to the α/β-hydrolase superfamily [1]. (clan SC).

Allergens from this family

15% of honeybee sensitized patients had IgE to Api m 9, a carboxypeptidase from bee venom.



  1. Holmquist M:
    Alpha/Beta-hydrolase fold enzymes: structures, functions and mechanisms.
    Curr Protein Pept Sci 2000, 1, 209-35. [PubMed]


Links to Pfam

Family-defining Pfam domains (at least one of these domains is present in each family member):

Pfam domain Pfam clan
PF00450 Serine carboxypeptidase CL0028 Alpha/Beta hydrolase fold
PF05388 Carboxypeptidase Y pro-peptide -

Links to Wikipedia


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