AF183: Insect pheromone-binding protein OS-D

List allergens from this family:

Routes of exposure:
Include only IUIS approved allergens.

Biochemical properties

Odorant-binding proteins are small, water-soluble proteins that solubilize hydrophobic odorant molecules to facilitate their transport to their receptors. The OS-D family is named after a protein identified in the antenna of Drosphila melanogaster. Homologues of OS-D are wide-spread among insects [1]. They share features with vertebrate odorant-binding proteins but show no sequence similarities.

Allergens from this family

Tha p 1, a major allergen from pine processionary caterpillar belongs to the OS-D family [2].



  1. Wanner KW, Willis LG, Theilmann DA, Isman MB, Feng Q, Plettner E:
    Analysis of the insect os-d-like gene family.
    J Chem Ecol 2004, 30, 889-911. [PubMed]
  2. Moneo I, Vega JM, Caballero ML, Vega J, Alday E:
    Isolation and characterization of Tha p 1, a major allergen from the pine processionary caterpillar Thaumetopoea pityocampa.
    Allergy 2003, 58, 34-7. [PubMed]


Links to Pfam

Family-defining Pfam domains (at least one of these domains is present in each family member):

Pfam domain Pfam clan
PF03392 Insect pheromone-binding family, A10/OS-D -

Links to Wikipedia


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