Transaldolase is an enzyme of the non-oxidative phase of the pentose phosphate pathway. It catalyzes the reversible transfer of dihydroxyacetone from sedoheptulose 7-phosphate to glyceraldehyde 3-phosphate, giving rise to erythrose 4-phosphate and fructose 6-phosphate.
Transaldolase was identified as cross-reactive mould allergen in Cladosporium cladosporioides (Cla c 14) and Penicillium chrysogenum (Pen ch 35) . These allergens showed cross-reactivity with the human enzyme.
Family-defining Pfam domains (at least one of these domains is present in each family member):
|Pfam domain||Pfam clan|
|PF00923||Transaldolase/Fructose-6-phosphate aldolase||CL0036||Common phosphate binding-site TIM barrel superfamily|
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