AF201: Actin-depolymerising factor homolog

List allergens from this family:

Routes of exposure:
Include only IUIS approved allergens.

Biochemical properties

This family defines an approximately 150 amino acid motif that is present in three phylogenetically distinct classes of eukaryotic actin-binding proteins [1]:

Allergens from this family

A cofilin from house dust mite, Der f 31, was identified as a minor allergen.



  1. Lappalainen P, Kessels MM, Cope MJ, Drubin DG:
    The ADF homology (ADF-H) domain: a highly exploited actin-binding module.
    Mol Biol Cell 1998, 9, 1951-9. [PubMed]


Links to Pfam

Family-defining Pfam domains (at least one of these domains is present in each family member):

Pfam domain Pfam clan
PF00241 Cofilin/tropomyosin-type actin-binding protein CL0092 Actin depolymerizing Factor

Links to Wikipedia


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