AF203: SCAI family

List allergens from this family:

Routes of exposure:
Include only IUIS approved allergens.

Biochemical properties

Members of this family are found in eukaryotes. Their functions are mostly unknown. One family member is SCAI (suppressor of cancer cell invasion), a transcriptional cofactor and tumour suppressor [1].

Allergens from this family

By screening a cDNA library, Tri a 43 was identified as a minor wheat allergen.



  1. Brandt DT, Baarlink C, Kitzing TM, Kremmer E, Ivaska J, Nollau P, Grosse R:
    SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.
    Nat Cell Biol 2009, 11, 557-68. [PubMed] [Full Text]


Links to Pfam

Family-defining Pfam domains (at least one of these domains is present in each family member):

Pfam domain Pfam clan
PF12070 Protein SCAI -


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