P18698-N15 Adaptive Designs - Evaluation and New Applications
 
Project
Abstract
Scientists/Scholars
Project Publications
Further Activities
Cooperations
Final Report

a) Peer-reviewed

[1] Bauer P (2006). Are Flexible Designs Sound? (Discussions). Biometrics 62 (3), 676–678.(pdf) ( http://www3.interscience.wiley.com/cgi-bin/fulltext/118626640/PDFSTART)

[2] Bauer P (2006). Survival endpoints and adaptive designs (Discussion). Biometrical Journal. 48(4):730-1. (pdf)

[3] Bauer P (2006). Methodological Developments vs. Regulatory Requirements. Biometrical Journal 48: 609-612.(pdf)

[4] Bauer P, Einfalt J (2006). Application of Adaptive Designs - a Review. Biometrical Journal 48: 493-506.(pdf)

[5] Brannath W, Koenig F, Bauer P (2006). Estimation in flexible two stage designs. Statistics in Medicine, 25(19): 3366-81.(pdf)

[6] Brannath W, Bauer P, Posch M (2006). On the efficiency of adaptive designs for flexible interim decisions in clinical trials. Journal of Statistical Planning and Inference, 136:1956-1961.(pdf)

[7] Bretz F, Schmidli H, König F, Racine A, Maurer W (2006). Confirmatory seamless phase II/III clinical trials with hypotheses selection at interim: General concepts (with discussion). Biometrical Journal, 48(4): 623-34(pdf)

[8] Bretz F, Schmidli H, König F, Racine A, Maurer W (2006). Rejoinder. Biometrical Journal, 48(4): 660-662.(pdf)

[9] Koenig F, Bauer P, Brannath W (2006). An adaptive hierarchical test procedure for selecting safe and efficient treatments (with discussion). Biometrical Journal, 48(4):663-78.(pdf)

[10] Koenig F, Bauer P, Brannath W (2006). Rejoinder. Biometrical Journal, 48(4): 693-694. (pdf)

[11] Brannath W, Koenig F, Bauer P (2007). Multiplicity and Flexibility in clinical trials. Pharmaceutical Statistics. 6(3):205-16. (pdf)

[12] Goll A, Bauer P (2007). Two-stage designs applying methods differing in costs. Bioinformatics. 23(12):1519-26. (pdf) ( http://bioinformatics.oxfordjournals.org/cgi/reprint/23/12/1519)

[13] Mehta CR, Bauer P, Posch M, Brannath W (2007). Repeated confidence intervals for adaptive group sequential trials. Statistics in Medicine. 26: 5422-5433 (pdf)

[14] Winkler W, Zellner M, Diestinger M, Babeluk R, Marchetti M, Goll A, Zehetmayer S, Bauer P, Rappold E, Miller I, Roth E, Allmaier G, Oehler R (2007). Biological variation of the platelet proteome in the elderly population and its implication for biomarker research. Mol Cell Proteomics. (pdf)

[15] Bauer P (2007). Adaptive designs: Looking for a needle in the haystack-A new challenge in medical research. Statistics in Medicine. 27:1565-80(pdf)

[16] Koenig F, Brannath W, Bretz F, Posch M (2007). Adaptive Dunnett Tests for Treatment Selection. Statistics in Medicine. 27:1612-25.(pdf)

[17] Posch M, Futschik A (2007). A uniform improvement of Bonferroni type tests by sequential tests. Journal of the American Statistical Association. 103(481):299-308.

[18] Posch, Wassmer, Brannath (2008). A note on repeated p-values for group sequential designs. Biometrika. 95:253-256. (pdf) ( http://biomet.oxfordjournals.org/cgi/reprint/asm080v1)

[19] Zehetmayer S, Bauer P, Posch M (2008) Optimized multi-stage designs controlling the False Discovery or the Family Wise Error Rate. Statistics in Medicine. 27:4145-60.(pdf)

[20] Brannath W, Mehta CR, Posch M (2009) Exact Confidence Bounds Following Adaptive Group Sequential Tests. Biometrics. To Appear.

[21] Bretz F, Koenig F, Brannath W, Glimm E, Posch M (2009) Adaptive designs for confirmatory clinical trials. Statistics in Medicine. To Appear.(pdf)

[22] Bretz F, Maurer W, Brannath W, Posch M (2009) A graphical approach to sequentially rejective multiple test procedures. Statistics in Medicine. To Appear.(pdf)

[23] Posch M, Zehetmayer S, Bauer P (2009) Hunting for Significance with the False Discovery Rate. Journal of the American Statistical Association. To Appear.

 

b) Non peer-reviewed

[1] Brannath W, König F, Posch M (2007). The scientific work of Peter Bauer. Biometrical Journal. 49(5):651-3.(pdf)

[2] Zehetmayer S, Goll A, Bauer P, Posch P (2007). Step by Step: mehr Effizienz mit neuen Studiendesigns. Biospektrum. 7:754-755.

[3] Posch M, Koenig F, Hsu J (2008) MCP2007-5th International Conference on Multiple Comparison Procedures. Biometrical Journal. 50(5):633-635 (pdf)

 

c) Stand-alone publications

Stand-alone publications

 

d) Publications for the general public and other publications

“Gene Analysis & Biostatistics - 3 is Better Than 2 But Not Than 4” ( http://www.fwf.ac.at/en/public_relations/press/pv200707-en.html).

“MedUni Wien: Internationale Konferenz beleuchtet die Zukunft neuer Herangehensweisen für medizinische Studien“ ( http://www.meduniwien.ac.at/files/4/6/pa_adaptive_designs.pdf).

 

 
 
 

With support from
FWFDer Wissenschaftsfonds