Matthias Gerlitz, MD
Department of Otorhinolaryngology
Position: Doctor-in-training
ORCID: 0009-0001-0542-9549
Keywords
Cochlea; Cochlear Implantation; Drug Delivery Systems; Hearing Loss
Research group(s)
- Christian Doppler Lab for Inner Ear Research
Head: Christoph Arnoldner
Research Area: This CD laboratory investigates the underlying mechanisms of inner ear diseases and researches various therapeutic approaches for the treatment of hearing loss. The high prevalence of hearing loss worldwide and the expected increase in hearing loss require innovative research strategies to improve patient care.
Members:
Research interests
My translational research work focuses on understanding the inner ear through a bench-to-bedsite approach. Using both in-vitro and in-vivo methods, my current research aims to improve cochlear implant outcomes, refine inner ear pharmacotherapy, and advance our understanding of processes inside the inner ear.
Selected publications
- Gerlitz, M. et al. (2024) ‘Insertion trauma of a novel inner ear catheter for intracochlear drug delivery’, Frontiers in Veterinary Science, 11. Available at: https://doi.org/10.3389/fvets.2024.1397554.
- Nieratschker, M. et al. (2024) ‘A preoperative dose of the pyridoindole AC102 improves the recovery of residual hearing in a gerbil animal model of cochlear implantation’, Cell Death & Disease, 15(7). Available at: https://doi.org/10.1038/s41419-024-06854-9.
- Yildiz, E. et al. (2023) ‘Investigation of inner ear drug delivery with a cochlear catheter in piglets as a representative model for human cochlear pharmacokinetics’, Frontiers in Pharmacology, 14. Available at: https://doi.org/10.3389/fphar.2023.1062379.
- Yildiz, E. et al. (2022) ‘Single-incision cochlear implantation and hearing evaluation in piglets and minipigs’, Hearing Research, 426, p. 108644. Available at: https://doi.org/10.1016/j.heares.2022.108644.
- Gadenstaetter, A.J. et al. (2023) ‘Functional Outcome After Simultaneous Vestibular Schwannoma Resection and Cochlear Implantation With Intraoperative Cochlear Nerve Monitoring’, Otolaryngology–Head and Neck Surgery, 168(6), pp. 1502–1510. Available at: https://doi.org/10.1002/ohn.233.