Center for Medical Data Science (Institute of Medical Statistics)
Position: Associate Professor
ORCID: 0000-0001-6863-7997
T +43 1 40400 74850
sonja.zehetmayer@meduniwien.ac.at
Keywords
Biostatistics; Epidemiology; Models, Statistical
Research interests
My main research focus is the design and analysis of clinical trials in medical statistics. The focus in statistical methodology is on the theory of multiple hypotheses testing controlling the FWER or FDR and on adaptive and group-sequential designs in the context of a clinical trial or in high-dimensional data.
Techniques, methods & infrastructure
An R-package for testing the global null hypothesis with the omnibus test is available (https://github.com/ThomasTaus/omnibus/blob/master/DESCRIPTION). An extended R-package including the test for subgroups is in preparation.
Grants
- eWHORM (2023)
Source of Funding: EU, Global Health EDCTP3
Coordinator of the collaborative project - Repeated Significance Tests controlling the False Discovery Rate (2009)
Source of Funding: FWF (Austrian Science Fund), Hertha Firnberg grant
Principal Investigator
Selected publications
- Zehetmayer, S., Posch, M. and Koenig, F. (2022) ‘Online control of the False Discovery Rate in group-sequential platform trials’, Statistical Methods in Medical Research, 31(12), pp. 2470–2485. Available at: http://dx.doi.org/10.1177/09622802221129051.
- Futschik, A., Taus, T. and Zehetmayer, S. (2018) ‘An omnibus test for the global null hypothesis’, Statistical Methods in Medical Research, 28(8), pp. 2292–2304. Available at: http://dx.doi.org/10.1177/0962280218768326.
- Zehetmayer, S., Graf, A.C. and Posch, M. (2015) ‘Sample size reassessment for a two-stage design controlling the false discovery rate’, Statistical Applications in Genetics and Molecular Biology, 14(5). Available at: https://doi.org/10.1515/sagmb-2014-0025.
- Zehetmayer, S., Posch, M. and Graf, A. (2022) ‘Impact of adaptive filtering on power and false discovery rate in RNA-seq experiments’, BMC Bioinformatics, 23(1). Available at: https://doi.org/10.1186/s12859-022-04928-z.
- Zehetmayer, S., Koenig, F. and Posch, M. (2024) ‘A general consonance principle for closure tests based on p-values’, Statistical Methods in Medical Research, 33(9), pp. 1595–1609. Available at: https://doi.org/10.1177/09622802241269624.