Detail

Keywords

Genomics; Host-Pathogen Interactions; Molecular Biology; Parasitology; Proteomics; Transcriptome

Research group(s)

• Molecular parasitology
  Head: Julia Walochnik
  Research Area: Acanthamoeba infections, amoebae as hosts for bacteria, vector-borne parasites, molecular phylogeny
  Members:
  Iwona Lesiak-Markowicz
  Martina Köhsler
  Rounik Mazumdar
  Alvie Loufouma Mbouaka
  Julia Walochnik
  Edwin Kniha

Grants

• Multi-omics to probe Acanthamoeba extracellular vesicles (2024)
  Source of Funding: FWF (Austrian Science Fund), ESPRIT
  Principal Investigator

Selected publications

1. Loufouma Mbouaka A, Lesiak-Markowicz I, Heredero-Bermejo I, Mazumdar R, Walochnik J and Martín-Pérez T (2023) Assessing Acanthamoeba cytotoxicity: comparison of common cell viability assays. Front. Microbiol. 14:1175469. doi: 10.3389/fmicb.2023.1175469
2. Loufouma Mbouaka A, Leitsch D, Koehsler M, Walochnik J. Antimicrobial effect of auranofin against Acanthamoeba spp. International Journal of Antimicrobial Agents. 2021 Nov;58(5):106425. DOI: 10.1016/j.ijantimicag.2021.106425. PMID: 34419578.
3. Leitsch, D., Loufouma Mbouaka, A., Köhsler, M. et al. An unusual thioredoxin system in the facultative parasite Acanthamoeba castellanii. Cell. Mol. Life Sci. 78, 3673–3689 (2021). https://doi.org/10.1007/s00018-021-03786-x
4. Köhsler M, Leitsch D, Loufouma Mbouaka A, Wekerle M, Walochnik J. Transcriptional changes of proteins of the thioredoxin and glutathione systems in Acanthamoeba spp. under oxidative stress - an RNA approach. Parasite. 2022;29:24. doi: 10.1051/parasite/2022025. Epub 2022 May 9. PMID: 35532265; PMCID: PMC9083255.
5. Loufouma Mbouaka, A. et al. (2021) ‘The elusive parasite: comparing macroscopic, immunological, and genomic approaches to identifying malaria in human skeletal remains from Sayala, Egypt (third to sixth centuries AD)’, Archaeological and Anthropological Sciences, 13(7). Available at: http://dx.doi.org/10.1007/s12520-021-01350-z.