Detail

Keywords

Brain Mapping; Depression; Functional Neuroimaging; Speech-Language Pathology

Research group(s)

• Brain Stimulation
  Head: Martin Tik
  Research Area: Martin Tik and his team specialize in transcranial magnetic stimulation (TMS) combined with functional magnetic resonance imaging (fMRI) to explore and modulate brain function. Their research discovered neural circuits involved in affective disorders, particularly depression. They utilize innovative approaches that integrate chronometric TMS with brain imaging. Collaborating with leading international institutions (Stanford, Toronto, Hongkong) they advance personalized brain stimulation therapy.
  Members:
  Onisim Soanca
  Martin Tik
  Rostyslav Samonov
  Maria Vasileiadi
  Sarah Grosshagauer
• Transcranial Magnetic Stimulation
  Head: Martin Tik
  Research Area: Transcranial magnetic stimulation (TMS) is a non-invasive method that uses magnetic pulses to induce activation in targeted brain regions. TMS has a vast parameter space, and optimizing these settings is crucial for effective treatment. Dr. Tik is a global pioneer in using neuroimaging, particularly functional MRI, and interleaved TMS-fMRI to refine TMS parameters. His work advances precision medicine by tailoring brain stimulation to individual patients, ensuring the most effective outcome.
  Members:
  Onisim Soanca
  Martin Tik
  Rostyslav Samonov
  Maria Vasileiadi
  Sarah Grosshagauer

Grants

• Improving presurgical language mapping through concurrent TMS-fMRI innovations (2021)
  Source of Funding: OeAW (Austrian Academy of Sciences), DOC PhD Stipend
  Principal Investigator

Selected publications

1. Vasileiadi, M. et al. (2023) ‘Functional connectivity explains how neuronavigated TMS of posterior temporal subregions differentially affect language processing’, Brain Stimulation, 16(4), pp. 1062–1071. Available at: https://doi.org/10.1016/j.brs.2023.06.014.
2. Grosshagauer, S. et al. (2024) ‘Chronometric TMS-fMRI of personalized left dorsolateral prefrontal target reveals state-dependency of subgenual anterior cingulate cortex effects’, Molecular Psychiatry, 29(9), pp. 2678–2688. Available at: https://doi.org/10.1038/s41380-024-02535-3.
3. Vasileiadi, M. et al. (2023) ‘Improved brain stimulation targeting by optimising image acquisition parameters’, NeuroImage, 276, p. 120175. Available at: https://doi.org/10.1016/j.neuroimage.2023.120175.
4. Tik, M. et al. (2023) ‘Concurrent TMS/fMRI reveals individual DLPFC dose-response pattern’, NeuroImage, 282, p. 120394. Available at: https://doi.org/10.1016/j.neuroimage.2023.120394.
5. Tik, M. et al. (2023) ‘Acute TMS/fMRI response explains offline TMS network effects – An interleaved TMS-fMRI study’, NeuroImage, 267, p. 119833. Available at: https://doi.org/10.1016/j.neuroimage.2022.119833.