Dose-Response Relationship, Radiation; Heavy Ions; Medical Physics; Quality Assurance, Health Care; Radiation Oncology; Risk Management
- Medical Radiation Research
Head: Dietmar Georg
Research Area: The vision of our group is the optimization of the treatment outcome of radiation oncology, alone or in combination with established chemotherapy or novel targeted strategies of drug treatment, with conventional photon or innovative ion-beams.
- Dose determination at the macroscopic and microscopic level
- Image guided precision radiotherapy with high energy photon beams
- MR guided radiation oncology
- Supervised decision making and workflow automation
- Proton, Carbon-ion and Helium-ion therapy
- Dose response effects at cellular and tissue level (pre-clinical and clinical)
Techniques, methods & infrastructure
- State-of-the-art photon beam linear accelerator with kV-based image guidance technology
- State-of-the-art treatment planning for photon, proton, Carbon ion and brachytherapy
- Comprehensive equipment for point dose, 2D and 3D dose measurements
- GATE/GEANT4 based Monte Carlo simulations
- Pre-clinical irradiator (kV beams) and pre-clinical imaging
- Scanned proton and Carbon ions beam with active energy variation (synchrotron)
- AI based on neural networks
- Image guided particle therapy of uveal melanoma with a multiport beam arrangement (2019)
Source of Funding: FFG (Austrian Research Promotion Agency), BRIDGE
- Proton and carbon ion response studies for chondrosarcoma – going beyond current radiobiological standards with 3D models (2019)
Source of Funding: FWF (Austrian Science Fund), Stand alone project
Coordinator of the collaborative project
- Magnetic resonance imaging guided proton therapy (2018)
Source of Funding: FWF (Austrian Science Fund), Programme Clinical Research (KLIF)
- Verhaegen, F. et al., 2018. ESTRO ACROP: Technology for precision small animal radiotherapy research: Optimal use and challenges. Radiotherapy and Oncology, 126(3), pp.471–478. Available at: http://dx.doi.org/10.1016/j.radonc.2017.11.016.
- Daniel, M. et al., 2017. Impact of hybrid PET/MR technology on multiparametric imaging and treatment response assessment of cervix cancer. Radiotherapy and Oncology, 125(3), pp.420–425. Available at: http://dx.doi.org/10.1016/j.radonc.2017.10.036.
- Fuchs, H. et al., 2017. Magnetic field effects on particle beams and their implications for dose calculation in MR-guided particle therapy. Medical Physics, 44(3), pp.1149–1156. Available at: http://dx.doi.org/10.1002/mp.12105.
- Georg, D., Knöös, T. & McClean, B., 2011. Current status and future perspective of flattening filter free photon beams. Medical Physics, 38(3), pp.1280–1293. Available at: http://dx.doi.org/10.1118/1.3554643.
- Georg, D. et al., 2008. Image-Guided Radiotherapy for Cervix Cancer: High-Tech External Beam Therapy Versus High-Tech Brachytherapy. International Journal of Radiation Oncology*Biology*Physics, 71(4), pp.1272–1278. Available at: http://dx.doi.org/10.1016/j.ijrobp.2008.03.032.