In the RNA Biology PhD track, RNA-based regulatory circuits are explored in silico, in vitro and in vivo with technologies ranging from bioinformatics over biochemistry to imaging.
RNAs mediate gene expression but have also regulatory, structural and signaling functions. Consequently, aberrant RNA processing, structure or function affects organismal development and health. Importantly, RNAs are heavilty modified to control its function but also immunogenicity. With the proper chemical modifications, RNAs can be developed into potent therapeutics such as the widely used mRNA-vaccines.
The doctoral program ‘RNA-Biology’ trains PhD candidates in basic- & biomedical research projects relevant to this topic and provides a state-of-the-art training environment.