The Christian Doppler Laboratory for Personalized Immunotherapy aims to provide a comprehensive 360° biomarker including various tissue-based, blood-based and radiology-based information of a particular patient for prediction of response to immune checkpoint-inhibition.
Our Vision: Individual Immunotherapy for each Individual
Immunotherapy of cancer represents a major breakthrough in oncology as long-term disease control can be achieved in some patients even in advanced disease stages. Immune checkpoint inhibitors activate the patient’s own immune system in order to enhance the anti-tumor immune reaction. However, only a fraction of patients responds to the currently available immunotherapies, while a clinically relevant fraction presents with primary resistance. Biomarkers reliably predicting which patients respond to immune checkpoint inhibitors are therefore urgently needed.
- Matthias Preusser
Principle Investigator of the Christian Doppler Laboratory for Personalized Immunotherapy
matthias.preusser@meduniwien.ac.at
PubMed - Anna Bergmeister-Berghoff
Senior-Post Doc
anna.bergmeister-berghoff@meduniwien.ac.at
PubMed - Timon Hofmann
Administration
timon.hofmann@meduniwien.ac.at - Erwin Tomasich
Wissenschaftlicher Mitarbeiter
erwin.tomasich@meduniwien.ac.at
PubMed - Angelika Starzer
MD
angelika.starzer@meduniwien.ac.at
PubMed - Carina Peischl
PhD Student
carina.peischl@meduniwien.ac.at - Julia Berger
MD PhD
julia.berger@meduniwien.ac.at - Andreas Kienzle
PhD
andreas.kienzle@meduniwien.ac.at - Markus Kleinberger
PhD
markus.kleinberger@meduniwien.ac.at
- Markus Raderer, Ao. Univ.-Prof. Dr.
Division of Oncology, Department of Medicine I
markus.raderer@meduniwien.ac.at - Thorsten Füreder, Assoc. Prof. Priv.-Doz. Dr.
Division of Oncology, Department of Medicine I
thorsten.fuereder@meduniwien.ac.at - Barbara Kiesewetter-Wiederkehr, Ap. Prof. Priv.-Doz. Dr. Dr.
Division of Oncology, Department of Medicine I
barbara.kiesewetter-wiederkehr@meduniwien.ac.at - Leonhard Müllauer, Ao. Univ.-Prof. Dr.
Department of Pathology
leonhard.muellauer@meduniwien.ac.at - Christoph Bock, Univ.-Prof.
CeMM and Institute of Artificial Intelligence and Decision Support
christoph.bock@meduniwien.ac.at - Klaus Schmetterer, Ap. Prof. Priv-Doz. Mag. DDr.
Department of Laboratory Medicine
klaus.schmetterer@meduniwien.ac.at - Harald Esterbauer, Assoc. Prof. Univ.Doz. DDr.
Department of Laboratory Medicine
harald.esterbauer@meduniwien.ac.at - Marius Mayerhöfer, Assoc. Prof. Priv.-Doz. Dr., PhD
Department of Biomedical Imaging and Image-guided Therapy
marius.mayerhoefer@meduniwien.ac.at - Georg Langs, Univ.-Prof. Dipl.-Ing. Dr.tech.
Department of Biomedical Imaging and Image-guided Therapy
georg.langs@meduniwien.ac.at - Michael Weber Mag. Dr.
Department of Biomedical Imaging and Image-guided Therapy
michael.weber@meduniwien.ac.at - Helmut Prosch, Assoc. Prof. Priv-Doz. Dr.
Department of Biomedical Imaging and Image-guided Therapy
helmut.prosch@meduniwien.ac.at
Tumor DNA methylation profiles correlate with response to anti-PD-1 immune checkpoint inhibitor monotherapy in sarcoma patients
https://pubmed.ncbi.nlm.nih.gov/33762319/
LAG-3 expression in the inflammatory microenvironment of glioma
https://pubmed.ncbi.nlm.nih.gov/33651248/
Circulating PD-L1 levels change during bevacizumab-based treatment in recurrent glioma
https://pubmed.ncbi.nlm.nih.gov/33956203/
Funding
The Christian Doppler Laboratory for Personalized Immunotherapy is supported by the funding program of the Christian Doppler Association in collaboration with Roche Austria.