Detail

Keywords

Algorithms; Optical Imaging; Tomography, Optical Coherence

Research group(s)

• Pircher Group
  Head: Michael Pircher
  Research Area: Adaptive optics optical coherence tomography, Retinal imaging, Corneal imaging, skin imaging.
  Members:
  Michael Pircher
  Elisabeth Brunner

Research interests

I am a postdoctoral researcher working on adaptive optics (AO) supported imaging of the human retina using optical coherence tomography (OCT). My research focuses on further developing ophthalmic AO and increasing its clinical applicability, amongst others by translating techniques from astronomical AO, such as the pyramid wavefront sensor and multi-conjugate adaptive optics. AO-OCT enables us to investigate the structure and function of the living retina at microscopic resolution and is an important tool to identify early biomarkers for retinal diseases such as age-related macular degeneration, glaucoma, or diabetic retinopathy.

Techniques, methods & infrastructure

• Adaptive optics
• Retinal imaging
• Optical Coherence Tomography
• Wavefront sensing and correction
• Numerical algorithms and optimization

Selected publications

1. Brunner, E. et al. (2021) ‘Retinal adaptive optics imaging with a pyramid wavefront sensor’, Biomedical Optics Express, 12(10), p. 5969. Available at: https://doi.org/10.1364/boe.438915.
2. Shirazi, M.F., Brunner, E., et al. (2020) ‘Visualizing human photoreceptor and retinal pigment epithelium cell mosaics in a single volume scan over an extended field of view with adaptive optics optical coherence tomography’, Biomedical Optics Express, 11(8), p. 4520. Available at: https://doi.org/10.1364/boe.393906.
3. Brunner, E. et al. (2018) ‘GPU implementation for spline-based wavefront reconstruction’, Journal of the Optical Society of America A, 35(6), p. 859. Available at: https://doi.org/10.1364/josaa.35.000859.
4. Viegers, M.,Brunner, E., et al. (2017) ‘Nonlinear spline wavefront reconstruction through moment-based Shack-Hartmann sensor measurements’, Optics Express, 25(10), p. 11514. Available at: https://doi.org/10.1364/oe.25.011514.