Detail

Keywords

Animal models; Bariatric Surgery; Fatty Liver; Fibrosis; Liver Regeneration

Research group(s)

• Metabolic and Bariatric Surgery
  Members:
  Claudia Ringhofer
  Julia Jedamzik
  Lisa Gensthaler
  Christoph Bichler
  Jakob Eichelter
  Felix Langer
  Daniel Moritz Felsenreich
  Magdalena Mairinger

Research interests

Clinical and preclinical studies in bariatric-metabolic surgery, evolution of MASH after bariatric-metabolic surgery, gut permeability in patients with obesity and after bariatric-metabolic surgery, non- invasive markers for fibrosis in patients with obesity, experimental animal models for regenerative medicine in basic science and clinical research 

Techniques, methods & infrastructure

Very experienced in the development of surgical rodent models.  

We have recently acquired and established an Ussing chamber with which electrophysiological flux and resistance measurements can be carried out, e.g. on the intestine.  

Grants

• Darmdurchlässigkeit in Patienten mit Fettlebererkrankung vor und nach Bariatrisch-Metabolischer Chirurgie - eine prospektive Kohortenstudie (2021)
  Source of Funding: Medical Scientific Fund of the Mayor of the City of Vienna, Medizinisch-Wissenschaftlichen Fonds des Bürgermeisters der Bundeshauptstadt Wien
  Principal Investigator
• Gut permeability and bariatric metabolic surgery (2021)
  Source of Funding: FWF (Austrian Science Fund), Elise- Richter Fellowship
  Principal Investigator

Selected publications

1. Eilenberg, M. et al., 2017. Significant Liver-Related Morbidity After Bariatric Surgery and Its Reversal—a Case Series. Obesity Surgery, 28(3), pp.812–819. Available at: http://dx.doi.org/10.1007/s11695-017-2925-x.
2. Eilenberg, M. et al., 2020. Long Term Evaluation of Nanofibrous, Bioabsorbable Polycarbonate Urethane Grafts for Small Diameter Vessel Replacement in Rodents. European Journal of Vascular and Endovascular Surgery, 59(4), pp.643–652. Available at: http://dx.doi.org/10.1016/j.ejvs.2019.11.004.
3. Eilenberg, M. et al. (2021) ‘Accuracy of non-invasive liver stiffness measurement and steatosis quantification in patients with severe and morbid obesity’, Hepatobiliary Surgery and Nutrition, 10(5), pp. 610–622. Available at: https://doi.org/10.21037/hbsn-20-787.
4. Jedamzik, J. et al., 2020. Impact of limb length on nutritional status in one-anastomosis gastric bypass: 3-year results. Surgery for Obesity and Related Diseases, 16(4), pp.476–484. Available at: http://dx.doi.org/10.1016/j.soard.2019.12.012.
5. Strobl, M. et al., 2013. Exhaled nitric oxide measurement to monitor pulmonary hypertension in a pneumonectomy-monocrotaline rat model. American Journal of Physiology-Lung Cellular and Molecular Physiology, 305(7), pp.L485–L490. Available at: http://dx.doi.org/10.1152/ajplung.00087.2013.