Keywords
Glioblastoma; Immunohistochemistry; Neurodegeneration
Research group(s)
- Baumann Lab
Head: Bernhard Baumann
Research Area: Develop multi-functional imaging techniques based in OCT for the preclinical diagnostic of Alzheimer's disease.
Members: - Adelheid Wöhrer
Head: Adelheid Woehrer
Research Area: Brain Tumors
Members:
Research interests
My main research focus lies on the connection between brain tumors and neurodegeneration as well as the connectivity with cellular senescence. I am mainly working on gliomas like glioblastoma, astrocytoma and oligodendroglioma. The title of my PhD thesis is called: "Decoding cellular senescence in glioblastoma".
Techniques, methods & infrastructure
- Immunhistochemistry and digital pathology
- single-cell RNA Sequencing
- Spatial Transcriptomics (Visium)
- Immunfluorescence
- Histology
- Brain tumor MRI
Selected publications
- Greutter, L. et al. (2024) ‘Frequent Alzheimer’s disease neuropathological change in patients with glioblastoma’, Neuro-Oncology Advances [Preprint]. Available at: https://doi.org/10.1093/noajnl/vdae118.
- Lichtenegger A, Tamaoki J, Licandro R, Mori T, Mukherjee P, Bian L, Greutter L, Makita S, Wöhrer A, Matsusaka S, Kobayashi M, Baumann B, Yasuno Y. Longitudinal investigation of a xenograft tumor zebrafish model using polarization-sensitive optical coherence tomography. Sci Rep. 2022 Sep 13;12(1):15381. doi: 10.1038/s41598-022-19483-z. PMID: 36100620; PMCID: PMC9470556.
- Semmler, L. et al. (2023) ‘Silk‐in‐Silk Nerve Guidance Conduits Enhance Regeneration in a Rat Sciatic Nerve Injury Model’, Advanced Healthcare Materials, 12(11). Available at: http://dx.doi.org/10.1002/adhm.202203237.
- Hainfellner, A. et al. (2024) ‘Glioblastoma in the real-world setting: patterns of care and outcome in the Austrian population’, Journal of Neuro-Oncology [Preprint]. Available at: https://doi.org/10.1007/s11060-024-04808-x.