Detail

Keywords

Clinical virology

Research interests

Our primary goal is to understand viral infection and replication pathways and to develop new and innovative diagnostic procedures in order to support clinical care. Viral infections in immunocompromised / immunosuppressed and guidance of immunosuprressive therapies as well as therapy of Hepatitis B / C and HIV.

Keywords
Viral infections in immunocompromised / immunosuppressed patients, antiviral therapy of viral infections (especially Hepatitis B and Hepatitis C). Respiratory viruses, Guidance of immunosuppression (Torque Teno Virus); Molecular and serological diagnostics; Development and validation of diagnostic methods, real-time PCR Viral infections in immunocompromised / immunosuppressed patients, antiviral therapy of viral infections (especially Hepatitis B and Hepatitis C). Respiratory viruses, Guidance of immunosuppression (Torque Teno Virus); Molecular and serological diagnostics; Development and validation of diagnostic methods, real-time PCR; Coronavirus SARS-CoV-2

Techniques, methods & infrastructure

Real-time PCR, serological assays (CLIA/CMIA) and cell culture techniques.

Selected publications

1. Strassl, R. et al., 2019. Torque Teno Virus for Risk Stratification of Acute Biopsy-Proven Alloreactivity in Kidney Transplant Recipients. The Journal of Infectious Diseases, 219(12), pp.1934–1939. Available at: http://dx.doi.org/10.1093/infdis/jiz039.
2. Strassl, R. et al., 2018. Quantification of Torque Teno Virus Viremia as a Prospective Biomarker for Infectious Disease in Kidney Allograft Recipients. The Journal of Infectious Diseases, 218(8), pp.1191–1199. Available at: http://dx.doi.org/10.1093/infdis/jiy306.
3. Mayer, F.J. et al., 2020. Development of a fully automated high throughput PCR for the detection of SARS-CoV-2: The need for speed. Virulence, 11(1), pp.964–967. Available at: http://dx.doi.org/10.1080/21505594.2020.1798041.
4. Strassl, R. et al., 2015. Real-Time PCR Assays for the Quantification of HCV RNA: Concordance, Discrepancies and Implications for Response Guided Therapy A. Kramvis, ed. PLOS ONE, 10(8), p.e0135963. Available at: http://dx.doi.org/10.1371/journal.pone.0135963.