Bacteriophages; Chemistry, Pharmaceutical; Extracellular Matrix Proteins; Inflammation; Molecular Mechanisms of Pharmacological Action; Single-Cell Analysis; Skin
- Tissue Homeostasis Group
Head: Karin Pfisterer
The main interests of my research group spread from changes in extracellular matrix organisation of inflammatory skin diseases to microbial homeostasis on healthy and pathological skin. We are focusing on determining the differences of the extracellular matrix and cytoskeleton of epidermal and dermal cells in chronic skin diseases like atopic dermatitis and psoriasis on a single cellular level. One of our research topics is also the penetration of aeroallergens through damaged skin lesions in patients with atopic dermatitis. Our most recent findings focus on the microbiological systems of the skin bioflora including bacteria, fungi and bacteriophages. As a master student of pharmacy I am mostly interested in developing new ideas for future therapeutics.
Techniques, methods & infrastructure
- Analytical chemistry
- Synthetical chemistry
- Molecular Biology techniques
- Cell and tissue culture
- Bacterial culture
- basic bioinformatic skills with R
- single cell RNA sequencing
- Wielscher, M. et al. (2022) ‘The Phageome in Normal and Inflamed Human Skin’, SSRN Electronic Journal [Preprint]. Available at: http://dx.doi.org/10.2139/ssrn.4294793.