Brain Stem; Cerebellum; Fetal Development; Fetal Diseases; Magnetic Resonance Imaging; Radiology
- Fetal magnetic resonance imaging
- Posterior fossa malformations
- Congenital heart defects
Techniques, methods & infrastructure
Fetal magnetic resonance imaging is a routinely performed and powerful diagnostic modality that enables a high-quality assessment of the growing fetus in vivo, starting with a gestational age of 18 weeks. It is a useful method, complementary to standard ultrasound examinations, where especially the brain parenchyma and body malformations can be assessed well. In the last decades there was a constant development and a significant improvement in MRI technique, leading to a better image quality and resolution. This opened the possibility to quantify subtle structures such as the cerebellum and brainstem. The prenatal posterior fossa is a challenging field of research with many different aspects (anatomical, embryological, and functional).
- Assessment of Brain Maturation in Fetuses with Congenital Heart Disease –a single center prospective fetal US and MRI stud (2020)
Source of Funding: Medical University of Vienna, Comprehensive center for pediatrics starter grant
- Dovjak, G.O. et al. (2022) ‘Brainstem and cerebellar volumes at MRI are smaller in fetuses with congenital heart disease’, American Journal of Obstetrics and Gynecology [Preprint]. Available at: http://dx.doi.org/10.1016/j.ajog.2022.03.030.
- Dovjak, G.O. et al. (2021) ‘Abnormal Extracardiac Development in Fetuses With Congenital Heart Disease’, Journal of the American College of Cardiology, 78(23), pp. 2312–2322. Available at: http://dx.doi.org/10.1016/j.jacc.2021.09.1358.
- Dovjak, G.O. et al. (2021) ‘Normal human brainstem development in vivo: a quantitative fetal MRI study’, Ultrasound in Obstetrics & Gynecology, 58(2), pp. 254–263. Available at: http://dx.doi.org/10.1002/uog.22162.
- Dovjak, G.O. et al. (2020) ‘Quantitative fetal magnetic resonance imaging assessment of cystic posterior fossa malformations’, Ultrasound in Obstetrics & Gynecology, 56(1), pp. 78–85. Available at: http://dx.doi.org/10.1002/uog.21890.
- Dovjak, G.O. et al. (2018) ‘Prenatal assessment of cerebellar vermian lobulation: fetal MRI with 3-Tesla postmortem validation’, Ultrasound in Obstetrics & Gynecology, 52(5), pp. 623–630. Available at: http://dx.doi.org/10.1002/uog.18826.