Animal Experimentation; Imaging, Three-Dimensional; Medical 3D-Printing; Neonatology; Patient Simulation; Tissue Engineering
- Additve Manufacturing for Medical Research - M3dRES
Research Area: The M3dRES project aims at establishing a unique infrastructure devoted to 3d-printing for medical research in a strongly interdisciplinary environment.
With a background in dentistry and implantology, I spent my initial years in research in establishing 3D oral micro-tissues as an alternative to animal testing and building blocks for bioprinting. My interest lies in developing 4D (smart) and 3D printed animal and human simulation models to replace, reduce and refine pre-clinical and clinical experiments. These models are used for designing and developing medical and dental devices, surgical planning and skill acquisition in human and veterinary medicine. We work in collaboration with various clinics to create 3D simulation models for skills training and preoperative planning. In parallel, we are constantly endeavouring to combat the problem of Cleft lip and palate (1:700 live births) in children belonging to low-economic areas of Asia, Africa and Europe. To address this issue, we have developed an affordable 3D printed physiological oral prosthesis called ‘Smart Obturator’. Ultimately, my aim is to utilize 3D printing to enhance the standard healthcare and escalate patient-safety.
- Wagner, M., Werther, T., Unger, E., Kasprian, G., Dovjak, G., Dorfer, C., Schned, H., Steinbauer, P., Goeral, K., Olischar, M., Roessler, K., Berger, A., & Oberoi, G. (2021). Development of a 3D printed patient-specific neonatal brain simulation model using multimodality imaging for perioperative management. Pediatric research, 10.1038/s41390-021-01421-w. Advance online publication. https://doi.org/10.1038/s41390-021-01421-w
- Hatamikia, S. et al., 2020. Additively Manufactured Patient-Specific Anthropomorphic Thorax Phantom With Realistic Radiation Attenuation Properties. Frontiers in Bioengineering and Biotechnology, 8. Available at: http://dx.doi.org/10.3389/fbioe.2020.00385.
- Oberoi, G. et al., 2018. 3D Printing—Encompassing the Facets of Dentistry. Frontiers in Bioengineering and Biotechnology, 6. Available at: http://dx.doi.org/10.3389/fbioe.2018.00172.
- Hatamikia, S. et al. (2022) ‘Additively manufactured test phantoms for mimicking soft tissue radiation attenuation in CBCT using Polyjet technology’, Zeitschrift für Medizinische Physik [Preprint]. Available at: http://dx.doi.org/10.1016/j.zemedi.2022.05.002.
- Oberoi, G. et al., 2020. Titanium dioxide-based scanning powder can modulate cell activity of oral soft tissue - Insights from in vitro studies with L929 cells and periodontal fibroblasts. Journal of Prosthodontic Research, 64(1), pp.34–42. Available at: http://dx.doi.org/10.1016/j.jpor.2019.05.001.