Acute Lung Injury; Clinical Trial; Intensive Care; Renin-Angiotensin System
My research focuses are clinical trials in critical care medicine, acute lung injury/acute respiratory distress syndrome and the renin-angiotensin-system in critical illness and the perioperative period. Currently, my research group is participating in the multicenter phase IIb trial on AP301/solnatide as inhalation therapy for ARDS.
- The angiotensin metabolite profile after subarachnoid hemorrhage (2021)
Source of Funding: FWF (Austrian Science Fund), KLIF
- Krenn, K. et al., 2017. Inhaled AP301 for treatment of pulmonary edema in mechanically ventilated patients with acute respiratory distress syndrome: a phase IIa randomized placebo-controlled trial. Critical Care, 21(1). Available at: http://dx.doi.org/10.1186/s13054-017-1795-x.
- Krenn, K. et al., 2015. Effects of azithromycin and tanomastat on experimental bronchiolitis obliterans. The Journal of Thoracic and Cardiovascular Surgery, 149(4), pp.1194-1202. Available at: http://dx.doi.org/10.1016/j.jtcvs.2014.11.088.
- Krenn, K. et al., 2007. Recipient Vascular Endothelial Growth Factor Serum Levels Predict Primary Lung Graft Dysfunction. American Journal of Transplantation, 7(3), pp.700-706. Available at: http://dx.doi.org/10.1111/j.1600-6143.2006.01673.x.