Detail

Keywords

Aneurysm; Antibiotic Prophylaxis; Clinical Trial; Heart Transplantation; Heart Valve Diseases; Heme Oxygenase-1; Ischemic Preconditioning; Microdialysis; Mitral Valve Annuloplasty; Pacemaker, Artificial

Research interests

• Heart valve disease: Ross procedure, bioprostheses, rapid-deployment valves, adjustable mitral rings, decellularized homografts, aortic valve reconstruction
• Clinical trials applying pharmacological approaches in cardiac surgery: Heme oxygenase - 1 induction, optimal perioperative antibiotic prophylaxis measured by microdialysis, selective endothelin blocker (BQ-123) during CABG surgery
• Biobanking: Heart transplant biobank for detection of rejection and cardiac allograft vasculopathy
• Aneurysms of the thoracic aorta: Defining genetic risk factors for the development of aneurysms
• Ischemia reperfusion injury: Development of a model to detect early effects of therapeutic approaches for ischemia - reperfusion injury in healthy subjects applying functional magnetic resonance imaging. 

Techniques, methods & infrastructure

• Clinical trials in heart valve surgery
• Microdialysis in cardiac surgery
• Heart transplant biobank

Selected publications

1. Andreas, M. et al., 2014. Comparable long-term results for porcine and pericardial prostheses after isolated aortic valve replacement. European Journal of Cardio-Thoracic Surgery, 48(4), pp.557-561. Available at: http://dx.doi.org/10.1093/ejcts/ezu466.
2. Andreas, M. et al., 2014. The Ross procedure offers excellent survival compared with mechanical aortic valve replacement in a real-world setting. European Journal of Cardio-Thoracic Surgery, 46(3), pp.409-414. Available at: http://dx.doi.org/10.1093/ejcts/ezt663.
3. Andreas, M. et al., 2014. A Single-Center Experience With the Ross Procedure Over 20 Years. The Annals of Thoracic Surgery, 97(1), pp.182-188. Available at: http://dx.doi.org/10.1016/j.athoracsur.2013.08.020.
4. Andreas, M. et al., 2013. Internal Mammary Artery Harvesting Influences Antibiotic Penetration Into Presternal Tissue. The Annals of Thoracic Surgery, 95(4), pp.1323-1330. Available at: http://dx.doi.org/10.1016/j.athoracsur.2012.10.088.
5. Andreas, M. et al., 2011. Effect of ischemic preconditioning in skeletal muscle measured by functional magnetic resonance imaging and spectroscopy: a randomized crossover trial. J Cardiovasc Magn Reson, 13(1), p.32. Available at: http://dx.doi.org/10.1186/1532-429X-13-32.