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Matthias Wielscher
Matthias Wielscher

Department of Dermatology
Position: Research Associate (Postdoc)

ORCID: 0000-0003-4138-1383
T +43 1 650 8641043


Data Interpretation, Statistical; Gene Expression Profiling; Genomics

Techniques, methods & infrastructure

  • Genetics: Variant calling and interpretation
  • Gene expression: read alignment, QC and counting
  • Gene expression: single cell RNA seq, RNA seq data analysis
  • Data integration: combining multipe datasets from differnent sources
  • Epidemiology: data cleaning, analysis and interpretation
  • Bioinformatics: large scale data analysis

Selected publications

  1. Wielscher, M. et al., 2020. Genetic correlation and causal relationships between cardio-metabolic traits and Lung function Impairment. Available at:
  2. Wielscher, M. et al., 2015. Diagnostic Performance of Plasma DNA Methylation Profiles in Lung Cancer, Pulmonary Fibrosis and COPD. EBioMedicine, 2(8), pp.929–936. Available at:
  3. Imboden, M. et al., 2019. Epigenome-wide association study of lung function level and its change. European Respiratory Journal, 54(1), p.1900457. Available at:
  4. Shrine, N. et al., 2019. New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nature Genetics, 51(3), pp.481–493. Available at:
  5. Matthias, W. et al., 2013. Cytosine 5-Hydroxymethylation of the LZTS1 Gene Is Reduced in Breast Cancer. Translational Oncology, 6(6), pp.715–IN27. Available at: