Detail

Keywords

Cell Biology; Microscopy; Neurobiology; Placenta

Research interests

My research background is molecular and cell biology, with focus on human trophoblast development and function. During my postdoctoral training at IST Austria I have focused on developing novel (super-resolution) light microscopy methods for living and fixed (brain) tissue.

Now I act as the head of the Core Facility Imaging and am happy to provide my expertise to researchers of the MedUni Vienna. 

Techniques, methods & infrastructure

Confocal Microscopes

Leica SP8 FALCON + Digital Lightsheet

Zeiss LSM 980 with Airyscan 2

Zeiss LSM 700

Olympus IXplore SpinSR (incl. SoRa Super Resolution Spinning Disk)

Widefield microscopes

Olympus IX83 widefield live cell microscope +TIRF module

Zeiss Axio Imager M2

Slide Scanner

Vectra Polaris (multispectral slide scanner)

TissueFAXs

Grants

• Epigenetische Regulation von Trophoblasten bei Präeklampsie (2018)
  Source of Funding: FWF (Austrian Science Fund), Erwin Schrödinger Fellowship
  Principal Investigator
• Epigentic regulation of trophoblats in severe preeclampsia (2018)
  Source of Funding: FWF (Austrian Science Fund), Erwin Schrödinger Fellowship
  Principal Investigator

Selected publications

1. Velicky, P., Miguel, E., Michalska, J.M. et al. Dense 4D nanoscale reconstruction of living brain tissue. Nat Methods 20, 1256–1265 (2023)
2. Michalska, J.M. et al. (2023) ‘Imaging brain tissue architecture across millimeter to nanometer scales’, Nature Biotechnology [Preprint]. Available at: http://dx.doi.org/10.1038/s41587-023-01911-8.
3. Velicky, P. et al., Genome amplification and cellular senescence are hallmarks of human placenta development. PLoS Genetics (2018)
4. Ben-Simon, Y. et al. (2022) ‘A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory’, Nature Communications, 13(1). Available at: http://dx.doi.org/10.1038/s41467-022-32559-8.