Center for Biomedical Research
Position: Research Associate (Postdoc)
ORCID: 0000-0002-9019-283X
T +43 1 40400 52240
sabrina.rohringer@gmx.at
Keywords
Cardiovascular; Cell Culture Techniques; Lymphangiogenesis; Mesenchymal Stromal Cells; Primary Cell Culture; Vascular Grafting
Research interests
My main research focus is to understand the healing process of small-diameter vascular grafts. I am focusing on the perivascular adipose tissue and how it can mediate the healing of different graft materials. Moreover, the importance of lymphangiogenesis during graft implantation is evaluated.
Techniques, methods & infrastructure
Vascular graft implantation: Abdominal aorta interposition model in rats
Post-implantation analyses: Histology, Scanning electron microscopy, Immunofluorescence staining, RT-qPCR, Western blot, Explant cultures, immune cell isolation
In vitro: Bio- and hemocompatibility assays, 2D and 3D cell culture models, immune cell activation assays, perfusion bioreactor systems
Selected publications
- Rohringer, S. et al. (2023) ‘Biodegradable, Self‐Reinforcing Vascular Grafts for In Situ Tissue Engineering Approaches’, Advanced Healthcare Materials, 12(23). Available at: https://doi.org/10.1002/adhm.202300520.
- Rohringer, S. et al. (2022) ‘Chorion-derived extracellular matrix hydrogel and fibronectin surface coatings show similar beneficial effects on endothelialization of expanded polytetrafluorethylene vascular grafts’, Materials Today Bio, 14, p. 100262. Available at: https://doi.org/10.1016/j.mtbio.2022.100262.
- Schneider, K.H. et al. (2020) ‘Riboflavin-mediated photooxidation to improve the characteristics of decellularized human arterial small diameter vascular grafts’, Acta Biomaterialia, 116, pp. 246–258. Available at: https://doi.org/10.1016/j.actbio.2020.08.037.
- Rohringer, S. et al. (2014) ‘Molecular and Cellular Effects of In Vitro Shockwave Treatment on Lymphatic Endothelial Cells’, PLoS ONE. Edited by J. Dulak, 9(12), p. e114806. Available at: https://doi.org/10.1371/journal.pone.0114806.
- Rohringer, S. et al. (2014) ‘Mechanisms of vasculogenesis in 3D fibrin matrices mediated by the interaction of adipose-derived stem cells and endothelial cells’, Angiogenesis, 17(4), pp. 921–933. Available at: https://doi.org/10.1007/s10456-014-9439-0.