Bone Development; Chiroptera; Developmental Biology; Histological Techniques; Imaging, Three-Dimensional; Reproductive Behavior
- Weninger Lab
Research Area: The focus of the Weninger lab rests on studying biomedical model organisms and human body donors with traditional dissection, innovative experimental approaches and cutting edge imaging technologies.
Techniques, methods & infrastructure
High Resolution Episcopic Microscopy (HREM) data sets from mouse strains generated within the Deciphering the Mechanisms of Developmental Disorders (DMDD) program are systematically evaluated to generate comparative data on normal and abnormal prenatal organ development.
Staining and embedding methods for HREM are adapted to new kinds of samples and refined to generate data sets faster.
- Grunstra, N.D.S. et al., 2019. Humans as inverted bats: A comparative approach to the obstetric conundrum. American Journal of Human Biology, p.e23227. Available at: http://dx.doi.org/10.1002/ajhb.23227.
- Gignac, P.M. et al., 2016. Diffusible iodine-based contrast-enhanced computed tomography (diceCT): an emerging tool for rapid, high-resolution, 3-D imaging of metazoan soft tissues. Journal of Anatomy, 228(6), pp.889-909. Available at: http://dx.doi.org/10.1111/joa.12449.
- Herdina, A.N. et al., 2015. Testing hypotheses of bat baculum function with 3D models derived from microCT. Journal of Anatomy, 226(3), pp.229-235. Available at: http://dx.doi.org/10.1111/joa.12274.
- Herdina, A.N. et al., 2015. Correlative 3D-imaging ofPipistrelluspenis micromorphology: Validating quantitative microCT images with undecalcified serial ground section histomorphology. Journal of Morphology, 276(6), pp.695-706. Available at: http://dx.doi.org/10.1002/jmor.20372.
- Herdina, A.N. et al., 2014. MicroCT Imaging Reveals Morphometric Baculum Differences for Discriminating the Cryptic SpeciesPipistrellus pipistrellusandP. pygmaeus. Acta Chiropterologica, 16(1), pp.157-168. Available at: http://dx.doi.org/10.3161/150811014X683372.