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Leopold Eckhart
Univ.-Prof. Dr. Leopold Eckhart

Department of Dermatology
Position: Associate Professor

ORCID: 0000-0002-5645-2036
T +43 1 40400 73735

Further Information


Apoptosis; Autophagy; Caspases; Endonucleases; Epidermis; Evolution, Molecular; Genomics; Keratinocytes; Keratins; Skin; Skin Diseases

Research group(s)

Research interests

  • Barrier function of the skin
  • Evolution of the skin
  • Programmed cell death
  • Autophagy
  • Genomics

Techniques, methods & infrastructure

  • Comparative genomics
  • Targeted gene deletions in animal models
  • In vitro models of human skin
  • Molecular biological, biochemical and immunohistochemical techniques


Selected publications

  1. Sukseree, S. et al. 2020. ATG7 is essential for secretion of iron from ameloblasts and normal growth of murine incisors during aging. Autophagy, 16(10), pp. 1851-1857. Available at:
  2. Feng, S. et al., 2020. Dense sampling of bird diversity increases power of comparative genomics. Nature, 587(7833), pp. 252-257. Available at:
  3. Strasser, B. et al., 2014. Evolutionary origin and diversification of epidermal barrier proteins in amniotes. Molecular Biology and Evolution, 31(12), pp.3194-3205. Available at:
  4. Fischer, H. et al., 2011. Essential role of the keratinocyte-specific endonuclease DNase1L2 in the removal of nuclear DNA from hair and nails. Journal of Investigative Dermatology, 131(6), pp.1208-1215. Available at:
  5. Eckhart, L. et al., 2008. Identification of reptilian genes encoding hair keratin-like proteins suggests a new scenario for the evolutionary origin of hair. Proceedings of the National Academy of Sciences, 105(47), pp.18419-18423. Available at: