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Detail

Alfred Gugerell
Mag. Dr. Alfred Gugerell

Department of Medicine II (Division of Cardiology)
Position: Research Associate (Postdoc)

ORCID: 0000-0002-5178-9967
T +43 1 40400 48530
alfred.gugerell@meduniwien.ac.at

Keywords

Cardiology; Culture Media, Conditioned; Fibrin; Imaging, Three-Dimensional; Mesenchymal Stem Cell Transplantation; Regenerative Medicine; Tissue Engineering

Research group(s)

  • Assoc. Prof. Dr. Mariann Pavone-Gyöngyösi

Research interests

As a human biologist (anthropology) my scientific background lies in the cell biology and molecular biology. My current research topic is cellular transformation in acute myocardial infarction in porcine in vivo models. Prior to that, I could gain experiences in soft tissue-engineering and wound-healing research as postdoc in the EU-project “Artivasc 3D” at the Division of Plastic and Reconstructive Surgery at the Medical University of Vienna (development of a three-layered skin substitute for burn wounds). My PhD thesis discussed the application of fibrin sealant in wound healing (Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and Baxter Bioscience).

Techniques, methods & infrastructure

  • Primary cell culture,
  • histology,
  • imaging
  • Flow cytometry,
  • RNA
  • proteins

Selected publications

  1. Lukovic, D. et al., 2017. Inhibition of CD34+ cell migration by matrix metalloproteinase-2 during acute myocardial ischemia, counteracted by ischemic preconditioning. F1000Research, 5, p.2739. Available at: http://dx.doi.org/10.12688/f1000research.9957.3.
  2. Gugerell, A. et al., 2014. Electrospun Poly(ester-Urethane)- and Poly(ester-Urethane-Urea) Fleeces as Promising Tissue Engineering Scaffolds for Adipose-Derived Stem Cells M. A. Barbosa, ed. PLoS ONE, 9(3), p.e90676. Available at: http://dx.doi.org/10.1371/journal.pone.0090676.
  3. Gugerell, A. et al., 2014. Thrombin as important factor for cutaneous wound healing: Comparison of fibrin biomatrices in vitro and in a rat excisional wound healing model. Wound Repair Regen, 22(6), pp.740-748. Available at: http://dx.doi.org/10.1111/wrr.12234.
  4. Gugerell, A. et al., 2014. Botulinum toxin A and lidocaine have an impact on adipose-derived stem cells, fibroblasts, and mature adipocytes in vitro. Journal of Plastic, Reconstructive & Aesthetic Surgery, 67(9), pp.1276-1281. Available at: http://dx.doi.org/10.1016/j.bjps.2014.05.029.
  5. Gugerell, A. et al., 2012. High thrombin concentrations in fibrin sealants induce apoptosis in human keratinocytes. Journal of Biomedical Materials Research Part A, 100A(5), pp.1239-1247. Available at: http://dx.doi.org/10.1002/jbm.a.34007.